Antioxidant and anti-inflammatory effects of fractions from ripe fruits of Solanum lycocarpum St. Hil. (Solanaceae) and putative identification of bioactive compounds by GC-MS and LC-DAD-MS

Autor: Melissa Grazielle Morais, Aline Aparecida Saldanha, Lucas Santos Azevedo, Iara Cotta Mendes, João Paulo Costa Rodrigues, Paula Avelar Amado, Katyuce de Souza Farias, Vanessa Samúdio Santos Zanuncio, Nadla Soares Cassemiro, Denise Brentan da Silva, Adriana Cristina Soares, Luciana Alves Rodrigues dos Santos Lima
Rok vydání: 2021
Předmět:
Zdroj: Food research international (Ottawa, Ont.). 156
ISSN: 1873-7145
Popis: Brazilian biodiversity includes species of the genus Solanum that have several biological activities, in addition to their relevance to agriculture, economics and popular medicine. The ripe fruits of Solanum lycocapum are an important nutritional food source, since they have levels of vitamin C, total soluble sugars, sucrose, phosphorus, and iron comparable or exceed the levels present in fruits such as pineapples, bananas, oranges, and mangoes. The pulp of the fruit is consumed by the population, and it is also used to produce jellies; to make marmalade, replacing the quince, and it can also be mixed with peaches in the preparation of peach. The objective of this study was to evaluate the anti-inflammatory and antioxidant activities of fractions obtained from the ripe fruits and to identify the constituents with these biological properties. The ripe fruits were collected, dried, crushed, and subjected to extraction by exhaustive percolation, obtaining an ethanol extract that was partitioned with solvents of increasing polarities, obtaining hexane (HEX), ethyl acetate (AC), and hydroethanol (HE) fractions. The AC fraction showed higher antioxidant potential compared to BHT (2,6-di-tert-butyl-4-methylphenol) and similar activity to AA (ascorbic acid) by DPPH (1,1-diphenyl-2-picrylhydrazyl) radical assay, while HEX and HE fractions exhibited of IC
Databáze: OpenAIRE