The effects of free condom distribution on HIV and other sexually transmitted infections in men who have sex with men

Autor: Bom, Reinier, van der Linden, Kalja, Matser, Amy, Poulin, Nicolas, van der Loeff, Maarten, Bakker, Bouko, van Boven, Theodoor
Přispěvatelé: Academic Medical Center, APH - Methodology, AII - Infectious diseases, Infectious diseases, APH - Global Health, Institut de Recherche Mathématique Avancée (IRMA), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
0301 basic medicine
Cost-Benefit Analysis
HIV Infections
law.invention
Men who have sex with men
Condoms
Gonorrhea
0302 clinical medicine
law
Medicine and Health Sciences
Medicine
030212 general & internal medicine
Chlamydia
Netherlands
Transmission (medicine)
Incidence
Incidence (epidemiology)
virus diseases
Hepatitis C
Infectious Diseases
Anti-Retroviral Agents
Cost effectiveness studies
Public Health
Research Article
Adult
Sexual transmission
030106 microbiology
Sexually Transmitted Diseases
lcsh:Infectious and parasitic diseases
03 medical and health sciences
Condom
Models/projections
Humans
lcsh:RC109-216
Syphilis
Homosexuality
Male
Models
Statistical
Behavioural interventions
business.industry
HIV
Community Health and Preventive Medicine
medicine.disease
Gonorrhoea
Prevention of sexual transmission
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
STI
business
Demography
Zdroj: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-10 (2019)
BMC infectious diseases, 19(1):222. BioMed Central
BMC Infectious Diseases
BMC Infectious Diseases, BioMed Central, 2019, 19 (1), pp.222. ⟨10.1186/s12879-019-3839-0⟩
ISSN: 1471-2334
DOI: 10.1186/s12879-019-3839-0
Popis: Background HIV and other sexually transmitted infections remain a burden on men who have sex with men in the era of effective combination antiretroviral therapy. New prevention efforts are therefore needed. One of these approaches is the current country-wide free condom distribution at gay bars with darkrooms and gay saunas in the Netherlands. This study assessed the effects of free condom distribution on incidence and burden of disease of HIV and other sexually transmitted infections. Methods A static model was constructed to calculate the impact of free condom distribution on HIV, hepatitis C, chlamydia, gonorrhoea, and syphilis among men who have sex with men visiting these venues. Outcomes included new infections averted and disability-adjusted life years averted. Scenario studies were performed to predict the effects of a further increase of condom use, condom effectiveness and coverage. Lastly, cost-effectiveness and sensitivity analyses were performed. Results Our model showed that condom use at public sex venues increased after the intervention. Annual incidence risk decreased, ranging from 5.73% for gonorrhoea to 7.62% for HIV. The annual number of new infections averted was largest for chlamydia and gonorrhoea (261 and 394 infections, respectively), but 42 new HIV infections were averted as well. In scenarios where condom use and condom effectiveness were further increased, the number of infections reduced more extensively. Over 99% of the decrease in burden of disease was due to HIV. The intervention was cost-effective and cost-saving (for every €1 spent on condom distribution, €5.51 was saved) and remained this in all sensitivity analyses. Conclusions Free condoms at public sex venues could reduce the transmission of HIV and other sexually transmitted infections. Condom distribution is an affordable and easily implemented intervention that could reduce the burden of disease in men who have sex with men substantially. Electronic supplementary material The online version of this article (10.1186/s12879-019-3839-0) contains supplementary material, which is available to authorized users.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje