Troponin T and NT ProBNP Levels in Gestational, Type 1 and Type 2 Diabetic Mothers and Macrosomic Infants
| Autor: | Mustafa Kurthan Mert, Hüseyin Selim Asker, Tamer Tetiker, Eren Kale Çekinmez, Fatma Tuncay Özgünen, Akgün Yaman, Mehmet Satar, Nazan Özbarlas |
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| Přispěvatelé: | Çukurova Üniversitesi |
| Rok vydání: | 2015 |
| Předmět: |
Cardiac function curve
Heart Defects Congenital Male medicine.medical_specialty Pediatrics Infant of diabetic mother Mothers 030204 cardiovascular system & hematology Umbilical cord Fetal Macrosomia 03 medical and health sciences 0302 clinical medicine Troponin T Pregnancy Internal medicine Natriuretic Peptide Brain Medicine Birth Weight Humans cardiovascular diseases Interventricular septum Prospective Studies 030219 obstetrics & reproductive medicine business.industry Infant Newborn Fetal Blood Peptide Fragments Cardiac surgery Diabetes Gestational medicine.anatomical_structure Macrosomic infant Echocardiography Metabolic control analysis Pediatrics Perinatology and Child Health Cardiology NT proBNP Gestation Arterial blood Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Pediatric cardiology. 37(1) |
| ISSN: | 1432-1971 |
| Popis: | PubMedID: 26266327 This study compares NT proBNP and troponin T levels in umbilical cord arterial blood and postnatal echocardiographic findings for infants of gestational and pregestational diabetic mothers and macrosomic infants. Twenty-seven infants of pregestational diabetic mothers, 61 infants of gestational diabetic mothers and 37 macrosomic infants of nondiabetic mothers were prospectively enrolled in this study along with a control group of 58 healthy infants of mothers without any pregestational or gestational disorders as the control group. All enrollees were born after 34 weeks of gestation. For this study, umbilical cord blood was drawn during delivery to determine NT proBNP and troponin T levels. Echocardiography was performed 24–72 h after the delivery. Umbilical cord troponin T and NT proBNP levels were found to be higher in the diabetic and macrosomic groups than in the control group (all of them p 6.1 %) metabolic control. In the good and suboptimal metabolic control diabetic groups, NT proBNP levels were also positively correlated with interventricular septum thickness (r = 0.536 and r = 0.576, respectively, p |
| Databáze: | OpenAIRE |
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