| Autor: |
Se Jin Jang, Daehyun Baek, Gu Kong, Eunsil Yu, Charles Lee, Eunho Yang, Hye Yoon Jang, Wang-rim Jung, Jong-eun Lee, Sun Young Lee, Farhan Haq, Deokhoon Kim, Joon Seon Song, Ji-Young Lee, Yong-Hee Kim, Sang-We Kim, Eun Kyung Choi, Sung-Min Chun, Chang-min Choi, Sung-Min Ahn, Sukjun Kim, Jongkyu Kim, Chang Ohk Sung, Hyeong Ryul Kim, Seongmin Choi |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1078-0432.22458326 |
| Popis: |
Supplementary Tables 1 - 15. Supp. Table 1. Sequenced reads per tumor and normal sample. Supp. Table 2. Comparison of significantly mutated genes detected using various MuTect thresholds. Supp. Table 3. Comparison of the number and rate of substitutions between never-smokers and smokers. Supp. Table 4. Comparison of various methods used to compute the background mutation rate. Supp. Table 5. Significantly mutated genes detected in our discovery cohort. Supp. Table 6. Comparison of significantly mutated genes and previously reported cancer driver genes. Supp. Table 7. Thirteen significantly altered CNV regions detected in our discovery cohort. Supp. Table 8. Druggable target candidates in the 22 significantly mutated genes and the 60 genes in the significantly altered CNV regions detected in the discovery cohort. Supp. Table 9. Pathways significantly enriched in the 22 significantly mutated genes and the 60 genes included in the significantly altered CNV regions that were detected in the discovery cohort. Supp. Table 10. Cox multivariable regression analysis for RB pathway alterations. Supp. Table 11. Cox univariable regression analysis of RB pathway alterations. Supp. Table 12. Comparison of mutations detected using whole-exome sequencing and Sequenom in selected genes. Supp. Table 13. Prevalence of known driver candidates when using two different MuTect parameters. Supp. Table 14. Number of patients included in the overall, tumor, node, and metastasis stage categories. Supp. Table 15. List of potential cancer driver genes with somatic substitutions or small indels determined in previous studies. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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