Pathogenesis and Treatment of Graft-Versus-Host Disease After Bone Marrow Transplant
| Autor: | Debra Bensen-Kennedy, Georgia B. Vogelsang, Linda Lee |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_treatment
Graft vs Host Disease chemical and pharmacologic phenomena Hematopoietic stem cell transplantation Disease General Biochemistry Genetics and Molecular Biology Donor lymphocyte infusion Pathogenesis Risk Factors immune system diseases Prednisone Humans Medicine Bone Marrow Transplantation business.industry Hematopoietic Stem Cell Transplantation General Medicine Prognosis medicine.disease Transplantation surgical procedures operative Graft-versus-host disease Acute Disease Chronic Disease Immunology Stem cell business Immunosuppressive Agents medicine.drug |
| Zdroj: | Annual Review of Medicine. 54:29-52 |
| ISSN: | 1545-326X 0066-4219 |
| DOI: | 10.1146/annurev.med.54.101601.152339 |
| Popis: | Stem cell transplantation is being used to treat a number of hematologic malignancies as well as hematologic and immune deficiency states. The ages of patients being offered this therapy and the donor marrow sources have been expanded. One persistent problem has been graft-versus-host disease (GVHD). This article reviews the basic biology of GVHD, clinical manifestations of acute and chronic GVHD, prophylaxis and treatment of acute GVHD, and treatment of chronic GVHD. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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