Spatial delivery of immune cues to lymph nodes to define therapeutic outcomes in cancer vaccination

Autor: James I. Andorko, Shannon J. Tsai, Joshua M. Gammon, Sean T. Carey, Xiangbin Zeng, Emily A. Gosselin, Camilla Edwards, Shrey A. Shah, Krystina L. Hess, Christopher M. Jewell
Rok vydání: 2023
Předmět:
Zdroj: Biomaterials science. 10(16)
ISSN: 2047-4849
Popis: Local signal integration in lymph nodes (LNs) controls the potency and selectivity of immune responses. Here, intra-LN depots were used to direct communication within treated LNs, causing programmable and divergent systemic immunotherapy outcomes.
Databáze: OpenAIRE