Oxygen Breathing Accelerates Decompression from Saturation at 40 msw in 70-kg Swine
| Autor: | Richard T. Mahon, Kathryn E Tucker, Shawn E. Soutiere, Kyle Petersen, Hugh M. Dainer |
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| Rok vydání: | 2010 |
| Předmět: |
Decompression
Male musculoskeletal diseases Swine business.industry Mixed gas Public Health Environmental and Occupational Health chemistry.chemical_element Decompression illness Decompression Sickness medicine.disease Oxygen Decompression sickness chemistry Anesthesia Oxygen breathing Respiration Animals Medicine business Saturation (chemistry) |
| Zdroj: | Aviation, Space, and Environmental Medicine. 81:639-645 |
| ISSN: | 0095-6562 |
| DOI: | 10.3357/asem.2681.2010 |
| Popis: | Introduction Submarine disaster survivors can be transferred from a disabled submarine at a pressure of 40 meters of seawater (msw) to a new rescue vehicle; however, they face an inherently risky surface interval before recompression and an enormous decompression obligation due to a high likelihood of saturation. The goal was to design a safe decompression protocol using oxygen breathing and a trial-and-error methodology. We hypothesized that depth, timing, and duration of oxygen breathing during decompression from saturation play a role to mitigate decompression outcomes. Methods Yorkshire swine (67-75 kg), compressed to 40 msw for 22 h, underwent one of three accelerated decompression profiles: (1) 13.3 h staged air decompression to 18 msw, followed by 1 h oxygen breathing, then dropout; (2) direct decompression to 18 msw followed by 1 h oxygen breathing then dropout; and (3) 1 h oxygen prebreathe at 40 msw followed by 1 h mixed gas breathing at 26 msw, 1 h oxygen breathing at 18 msw, and 1 h ascent breathing oxygen. Animals underwent 2-h observation for signs of DCS. Results Profile 1 (14.3 h total) resulted in no deaths, no Type II DCS, and 20% Type I DCS. Profile 2 (2.1 h total) resulted in 13% death, 50% Type II DCS, and 75% Type I DCS. Profile 3 (4.5 h total) resulted in 14% death, 21% Type II DCS, and 57% Type I DCS. No oxygen associated seizures occurred. Discussion Profile 1 performed best, shortening decompression with no death or severe DCS, yet it may still exceed emergency operational utility in an actual submarine rescue. |
| Databáze: | OpenAIRE |
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