Carbohydrate supplementation attenuates decrement in performance in overtrained rats

Autor: Caio Victor Coutinho de Oliveira, Nayara Moreira Lacerda Massa, Edilamar Menezes de Oliveira, Gustavo da Silva Félix, Carlos Vinícius da Silva Barbosa, Reabias de Andrade Pereira, Jailane de Souza Aquino, Alexandre Sérgio Silva
Rok vydání: 2015
Předmět:
0301 basic medicine
Male
Hydrocortisone
Physiology
Endocrinology
Diabetes and Metabolism
Running
chemistry.chemical_compound
Glycogen Synthase Kinase 3
Phosphatidylinositol 3-Kinases
0302 clinical medicine
Malondialdehyde
Ingestion
Testosterone
Treadmill
Creatine Kinase
Nutrition and Dietetics
biology
General Medicine
medicine.symptom
medicine.medical_specialty
Anorexia
03 medical and health sciences
Physiology (medical)
Internal medicine
Physical Conditioning
Animal
medicine
Dietary Carbohydrates
Animals
Rats
Wistar
Muscle
Skeletal
business.industry
Overtraining
Body Weight
RATOS WISTAR
030229 sport sciences
Carbohydrate
medicine.disease
Rats
030104 developmental biology
Endocrinology
chemistry
Dietary Supplements
biology.protein
Physical therapy
Physical Endurance
Creatine kinase
business
Proto-Oncogene Proteins c-akt
Zdroj: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
ISSN: 1715-5320
Popis: Carbohydrate ingestion at the end of a single exercise is recognized as delaying fatigue and accelerating recovery, but whether chronic ingestion can prevent overtraining during periods of intense training has not yet been elucidated. This study aimed to determine whether carbohydrate supplementation minimizes overtraining in Wistar rats. The animals underwent 11 weeks of training (running) on a treadmill, and the last 3 weeks were designed to induce overtraining. One group was supplemented with carbohydrates (EX-CHO) (n = 13), 1 group had no supplementation (EX) (n = 10), and a third group remained inactive (C) (n = 9). Performance tests were given before training (Pr1) and at the 8th (Pr2) and 11th (Pr3) training week. Food intake, body weight, testosterone, cortisol, malondialdehyde, creatine kinase, and activities of the PI3-K, Akt-1, mTOR, and GSK-3 enzymes were measured. In the EX group, there was a significant 32.6% performance decrease at Pr3 when compared with Pr2. In addition, at protocol completion, the EX-CHO group had a greater gastrocnemius weight than did the C group (p = 0.02), which the EX group did not. Training caused anorexia, decreased testosterone (p = 0.001), and increased malondialdehyde (p = 0.009) in both exercise groups compared with the C group, with no influence of carbohydrate supplementation on these variables (p > 0.05). Compared with in the C group, the activity of Akt-1 was higher in the EX-CHO group but not in the EX group (p = 0.013). Carbohydrate supplementation promoted an attenuation in the performance decrement and maintained gastrocnemius muscle mass in animals that had undergone overtraining protocols, which was accompanied by increased activity of the Akt-1 molecular indicator.
Databáze: OpenAIRE
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