Regional citrate anticoagulation for continuous renal replacement therapy in children
| Autor: | Ricardo Gastelbondo Amaya, Hernando Mulett Hoyos, Ana Maria Quintero Gómez, Mayerly Prada Rico, Daniel Tibaduiza, Jaime Fernández Sarmiento, Ana María Rojas Velasquez, Luz Stella González Chaparro |
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| Rok vydání: | 2016 |
| Předmět: |
Nephrology
Male medicine.medical_specialty Continuous renal replacement therapy Adolescent Critical Care medicine.medical_treatment Population 030232 urology & nephrology Hemorrhage 030204 cardiovascular system & hematology Citric Acid Cohort Studies 03 medical and health sciences Anticoagulation 0302 clinical medicine Internal medicine Hemofiltration medicine Humans Renal replacement therapy education Child Children Blood Coagulation Dialysis Retrospective Studies education.field_of_study business.industry Heparin Hazard ratio Anticoagulants Infant Retrospective cohort study Acute Kidney Injury Surgery Renal Replacement Therapy Anesthesia Child Preschool Pediatrics Perinatology and Child Health Female business Citrate medicine.drug |
| Zdroj: | Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana Repositorio Universidad de la Sabana Universidad de la Sabana instacron:Universidad de la Sabana |
| ISSN: | 1432-198X |
| Popis: | 9 páginas Background Anticoagulation of the continuous renal replacement therapy (CRRT) circuit is an important technical aspect of this medical procedure. Most studies evaluating the efficacy and safety of citrate use have been carried out in adults, and little evidence is available for the pediatric patient population. The aim of this study was to compare regional citrate anticoagulation versus systemic heparin anticoagulation in terms of the lifetime of hemofilters in a pediatric population receiving CRRT at a pediatric center in Bogota, Colombia. Methods This was an analytical, observational, retrospective cohort study in which we assessed the survival of 150 hemofilters (citrate group 80 hemofilters, heparin group 70 hemofilters) used in a total of 3442 hours of CCRT (citrate group 2248 h, heparin group 1194 h). Hemofilter survival was estimated beginning at placement and continuing until filter replacement due to clotting or high trans-membrane pressures. Results Hemofilter survival was higher in the citrate group than in the heparin group (72 vs. 18 h; p |
| Databáze: | OpenAIRE |
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