Crystalline arthropathy and bone health
| Autor: | Ian Chang, David Gazeley |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Crystal Arthropathies Gout Inflammatory arthritis 030209 endocrinology & metabolism Chondrocalcinosis Disease Hyperuricemia Lower risk Bone and Bones 03 medical and health sciences chemistry.chemical_compound Fractures Bone 0302 clinical medicine Rheumatology Bone Density Internal medicine medicine Humans 030203 arthritis & rheumatology business.industry Calcium pyrophosphate medicine.disease Uric Acid Osteopenia chemistry Meta-analysis business |
| Zdroj: | Current opinion in rheumatology. 30(2) |
| ISSN: | 1531-6963 |
| Popis: | Purpose of review The purpose of this review is to provide insight on the proposed association between crystal arthritis and bone health. Crystal arthritis is the most common type of inflammatory arthritis, and fractures contribute to significant morbidity and mortality, therefore, the relationship between the two is of clinical importance. Recent findings There have been variable findings regarding hyperuricemia, low bone density and risk of fracture. A recent systematic review and meta-analysis of available literature showed a correlation between increased serum uric acid and lower risk of fracture. Less is known about calcium pyrophosphate deposition disease and bone health, although two large studies have suggested an association with osteopenia. Summary A systematic review and meta-analysis of available data suggest a correlation between increased serum uric acid and lower risk of fracture. Findings support an association between bone health and crystal arthritis which warrants further study and may have implications for how we treat gout. |
| Databáze: | OpenAIRE |
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