The Effectiveness of Tuina in Relieving Pain, Negative Emotions, and Disability in Knee Osteoarthritis: A Randomized Controlled Trial
| Autor: | Hui Xu, Chi Zhao, Guangxin Guo, Yulin Li, Xinyu A, Guowei Qiu, Yuxia Wang, Bingxin Kang, Xirui Xu, Jun Xie, Lianbo Xiao |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Pain Medicine. 24:244-257 |
| ISSN: | 1526-4637 1526-2375 |
| DOI: | 10.1093/pm/pnac127 |
| Popis: | Objective To evaluate the effectiveness of Tuina in relieving the pain, negative emotions, and disability of patients with knee osteoarthritis (KOA). Design Single-center, parallel, randomized controlled trial. Setting Shanghai Guanghua Integrated Chinese and Western Medicine Hospital, Shanghai, China. Subjects Adult patients with KOA who were able to speak Chinese and self-report symptoms were eligible. Methods A total of 104 patients were randomly allocated to receive the 6-week treatment of Tuina (Tuina group) or celecoxib (celecoxib group). Data on pain, negative emotions, and disability were collected at baseline, at week 2, 4, and 6, and follow-up (1 month after the last treatment). The primary outcomes were the pressure pain thresholds. The secondary outcomes were: (1) numerical rating scale at rest and with movement; (2) Hamilton Anxiety Scale; (3) Hamilton Depression Scale; (4) Western Ontario and McMaster Universities Osteoarthritis Index; and (5) clinical effective rate. The adverse events of the trial were evaluated. Results In total, 99 patients completed the follow-up. Generalized linear mixed models were constructed to analyse the between-group differences. Statistically significant differences were found in the interaction effects (P Conclusions Tuina produced superior effects for pain, negative emotions, and disability over time, as compared to celecoxib in patients with KOA. |
| Databáze: | OpenAIRE |
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