Quantitative ultrasound assessment of the effect of parity on bone mineral density in females
| Autor: | Maissa Tirsen, Ahad E. Alotaibi, Norah Al-Batati, Samar AbuAlsaud, Deena Bakhder, Aram AlZahrani, H.I. Al-Mohammed, Ruba AlSubaie, Shahnaz Akil |
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| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty Osteoporosis Breastfeeding Absorptiometry Photon Females Bone Density Pregnancy Ultrasound Bone mineral density medicine Humans Prospective Studies Prospective cohort study Ultrasonography Bone mineral business.industry Obstetrics Confounding Obstetrics and Gynecology Gynecology and obstetrics General Medicine Middle Aged medicine.disease Osteopenia Parity Reproductive Medicine RG1-991 Female Public aspects of medicine RA1-1270 business Parity (mathematics) Research Article |
| Zdroj: | BMC Women's Health, Vol 21, Iss 1, Pp 1-6 (2021) BMC Women's Health |
| ISSN: | 1472-6874 |
| DOI: | 10.1186/s12905-021-01516-w |
| Popis: | Background The effect of pregnancy and breastfeeding on a female’s bone mineral density (BMD) is controversial. This prospective study aims to investigate the effect of parity on BMD among pre-menopausal multiparous females using quantitative ultrasound as a screening method and females with no pregnancies (nulliparous) as a control group. Methods A portable ultrasound-based bone densitometer (DMS PEGASUS SMART, Mauguio, France) was used to indirectly assess the BMD in 51 multiparous (29–45 years) and 51 nulliparous Arabic females (18–35 years) by quantifying the broadband ultrasound attenuation (BUA) from their right calcaneus bone. BUA > 70 db/mhz = normal, BUA 65–69.9 db/mhz = below average, BUA 55–64.9 db/mhz = osteopenia and BUA Results There was a significant difference in mean BUA between multiparous and nulliparous females (74.1 db/mhz vs. 69.3 db/mhz, p = 0.006). The prevalence of normal BMD was significantly higher in the nulliparous group than in the multiparous group (70.6% vs. 47.1%, p = 0.02). Osteoporosis was found in the multiparous group only (3/51). Among the multiparous females who breastfed (43/51), a total of 51.2% (22/43) had normal BMD, 25.6% (11/43) had BMD below average, 18.6% (8/43) had osteopenia and 4.7% (2/43) had osteoporosis. No significant differences in mean BUA (p = 0.2) were found between the group of females who breastfed for one year (13/43; BUA: 70.5 ± 9.4), the group of females who breastfed for 6–11 months (8/43; BUA: 70.6 ± 10.0) and those who breastfed for less than six months (22/43; BUA: 71.6 ± 9.4). A binary logistic regression model built for predicting BMD normality showed significance for the variable parity (p = 0.03), while the effect of the possible confounding variables BMI and age on BMD normality was found to be non- significant (p = 0.1 and p = 0.6, respectively). Conclusion Parity affects the BMD, as assessed by a portable ultrasound-based bone densitometer, of young and middle-aged females as compared to the BMD of nulliparous females. |
| Databáze: | OpenAIRE |
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