Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia
| Autor: | Tetsufumi Kanazawa, Hiroshi Yoneda, Hiroki Kikuyama, Takehiko Okamura, Seiichiro Tarutani, Munehiro Ohta |
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| Rok vydání: | 2015 |
| Předmět: |
Questionnaires
medicine.medical_specialty Medication adherence Economic shortage Logistic regression 03 medical and health sciences 0302 clinical medicine Internal medicine Outpatients medicine Psychiatric hospital In patient Psychiatry Biological Psychiatry business.industry Questionnaire medicine.disease 030227 psychiatry Critical period Psychiatry and Mental health Schizophrenia Original Article Medication rate business 030217 neurology & neurosurgery |
| Zdroj: | Psychiatry Investigation |
| ISSN: | 1738-3684 |
| Popis: | Objective Medication adherence is important in the treatment of schizophrenia, and critical periods during treatment may be associated with relapse. However, the relationship between adherence and duration of outpatient treatment (DOT) remains unclear. The authors aimed to clarify the relationship between adherence and DOT at a psychiatric hospital in Japan. Methods For outpatients with schizophrenia who regularly visit Shin-Abuyama hospital, the authors conducted a single questionnaire survey (five questions covering gender, age, DOT, medication shortages, and residual medication) over one month period. Participants were divided into two groups whether DOT were from more than one year to within five years or not. Mantel-Haenszel analysis and logistic regression analysis were performed on the data regarding the medication adherence. Results Effective answers were received for 328 patients. The residual medication rate was significantly higher among those receiving outpatient treatment from more than one year to within five years than five years than those receiving outpatient treatment for more than five years or less than one year (p=0.016). Conclusion This survey suggests that there are critical periods during which patients are most prone to poor adherence. Because poor adherence increases the risk of relapse, specific measures must be taken to improve adherence during these periods. |
| Databáze: | OpenAIRE |
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