Perimenopausal giant hydatidiform mole complicated with preeclampsia and hyperthyroidism: A case report and literature review
| Autor: | Ying Jin, Guoqing Jiang, Zengping Hao, Yan Wan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
giant hydatidiform mole
endocrine system medicine.medical_specialty endocrine system diseases medicine.medical_treatment Case Report Human chorionic gonadotropin Preeclampsia preeclampsia 03 medical and health sciences 0302 clinical medicine Serum hcg Mole hyperthyroidism Medicine 030212 general & internal medicine reproductive and urinary physiology Gynecology Chemotherapy 030219 obstetrics & reproductive medicine Hysterectomy business.industry Gestational trophoblastic disease General Medicine medicine.disease perimenopausal embryonic structures Gestation business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Open Medicine Open Medicine, Vol 16, Iss 1, Pp 1038-1042 (2021) |
| ISSN: | 2391-5463 |
| DOI: | 10.1515/med-2021-0315 |
| Popis: | Gestational trophoblastic disease (GTD) commonly occurs in reproductive females, but is extremely rare in perimenopausal females. In this study, we reported a case of hydatidiform mole in a 48-year-old perimenopausal female admitted due to a giant uterine mass of 28 weeks’ gestational size. The serum human chorionic gonadotropin (HCG) level ranged from 944 to 1,286 mIU/mL before treatments. The signs of preeclampsia and hyperthyroidism were relatively prominent. Hysterectomy was performed and chemotherapy was scheduled when the serum HCG level remained at a plateau, about 528 mIU/mL. The symptoms of preeclampsia and hyperthyroidism were relieved after treatment. Accordingly, we concluded that GTD could occur in perimenopausal woman and hysterectomy usually is the optimal treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|