XtalPiMS: A PiMS-based web application for the management and monitoring of crystallization trials
| Autor: | Ian Berry, Chris Morris, J.M. Diprose, Keith S. Wilson, David I. Stuart, Robert Esnouf, Raymond J. Owens, Ed Daniel, Richard Blake, Susanne L. Griffiths, B Lin |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Information management
Computer science Information Management computer.software_genre Crystallography X-Ray Online Systems Article law.invention Data management and databases 03 medical and health sciences User-Computer Interface Robotic imagers law Structural Biology Web application Laboratory Information Management Systems (LIMS) Crystallization Layer (object-oriented design) Databases Protein 030304 developmental biology 0303 health sciences Database business.industry Java web application 030302 biochemistry & molecular biology Proteins Robotics Management information systems Embedded system Database Management Systems Artificial intelligence User interface business Protein crystallization computer |
| Zdroj: | Journal of Structural Biology |
| ISSN: | 1095-8657 1047-8477 |
| Popis: | A major advance in protein structure determination has been the advent of nanolitre-scale crystallization and (in a high-throughput environment) the development of robotic systems for storing and imaging crystallization trials. Most of these trials are carried out in 96-well (or higher density) plates and managing them is a significant information management challenge. We describe xtalPiMS, a web-based application for the management and monitoring of crystallization trials. xtalPiMS has a user-interface layer based on the standards of the Protein Information Management System (PiMS) and a database layer which links the crystallization trial images to the meta-data associated with a particular crystallization trial. The user interface has been optimized for the efficient monitoring of high-throughput environments with three different automated imagers and work to support a fourth imager is in progress, but it can even be of use without robotics. The database can either be a PiMS database or a legacy database for which a suitable mapping layer has been developed. © 2011 Elsevier Inc. |
| Databáze: | OpenAIRE |
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