Circulating levels of the adipocytokines vaspin and omentin in patients with Kawasaki disease
Autor: | Luca Cantarini, Rolando Cimaz, Marta Generoso, Mauro Galeazzi, Maria Romana Bacarelli, Gabriele Simonini, Antonella Fioravanti |
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Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty Disease onset Immunology Adipokine Enzyme-Linked Immunosorbent Assay Mucocutaneous Lymph Node Syndrome GPI-Linked Proteins Gastroenterology Adipokines Rheumatology Lectins Internal medicine medicine Humans Immunology and Allergy In patient Child IVIG Therapy Serpins Analysis of Variance Aspirin business.industry Infant medicine.disease Italy Intravenous Immunoglobulins Case-Control Studies Child Preschool Cytokines Female Kawasaki disease business medicine.drug |
Zdroj: | Rheumatology International. 32:1481-1482 |
ISSN: | 1437-160X 0172-8172 |
Popis: | Methods Our study group included 21 children (14 male, 7 female) with KD classified as complete on the basis of published standard clinical Criteria. The KD patients were enrolled within the 7th day from disease onset, with day 1 defined as the first day of fever symptoms. Serial blood samples were obtained from all KD patients in the acute phase before the IVIG therapy. Serum vaspin and omentin were analyzed by ELISA assays. All patients were administered both aspirin (30-50 mg/kg/day) and a single dose of intravenous immunoglobulins (IVIGs) (2 g/kg). Twentyfive healthy children (15 male, 10 female) were enrolled as controls. |
Databáze: | OpenAIRE |
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