Is a predominant left-to-right shunt associated with migraine?: A prospective atrial septal defect closure study
| Autor: | Maarten J. Suttorp, Werner Budts, Justin G.L.M. Luermans, Martijn C. Post, Jurriën M. ten Berg, Vincent Thijs, Frederik Temmerman, H. W. Thijs Plokker, Wouter J. Schonewille |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Migraine without Aura Pediatrics medicine.medical_specialty Cardiac Catheterization Percutaneous Time Factors Aura Septal Occluder Device medicine.medical_treatment Migraine with Aura Heart Septal Defects Atrial Belgium Surveys and Questionnaires medicine Prevalence Humans Radiology Nuclear Medicine and imaging Prospective Studies Prospective cohort study Cardiac catheterization Netherlands Heart septal defect business.industry Hemodynamics General Medicine Middle Aged medicine.disease Migraine with aura Echocardiography Doppler Treatment Outcome Migraine Patent foramen ovale Female medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 74(7) |
| ISSN: | 1522-726X |
| Popis: | Background: A right-to-left shunt, as seen in patients with a patent foramen ovale, seems to be associated with migraine. An atrial septal defect (ASD), however, is characterized by a predominant left-to-right shunt (LRS). We prospectively evaluated the effect of percutaneous ASD closure on migraine Methods: All 70 consecutive patients (>16 years) who underwent a percutaneous ASD closure between November 2003 and December 2005 in one of the two participating centers were included in the study. On the basis of standardized headache questionnaire, two independent neurologists diagnosed migraine with or without aura (MA+ and MA−, respectively) according to the International Headache Society criteria, before, 6 and 12 months after closure. Results: Sixty-eight patients (97%; mean age 47.3 ± 16.4 years; 22% men) agreed to participate in the study and completed the questionnaire. Before ASD closure, the overall prevalence of migraine was 34%, MA+ 22% and MA− 12%. At 6 months follow-up, the headache questionnaire was completed by 63 patients (93%) and the prevalence of overall migraine decreased to 19%, MA+ to 8% and MA− to 11% (Mc Nemar test, P = 0.08, P = 0.07, and P = 1.0, respectively). At 12 months, the prevalence of migraine decreased further to 12%, MA+ to 5% and MA− to 7% (McNemar test, P = 0.003, P = 0.04, and P = 0.29 versus at inclusion, respectively) based on a completed headache questionnaire of 57 patients (84%). Conclusion: We found a high prevalence of migraine in patients with an ASD, and observed prospectively a reduction in the occurrence of migraine, especially migraine with aura, 1 year after percutaneous closure. © 2009 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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