O-(Fluoresceinylmethyl)hydroxylamine (OFMHA): a reagent for the preparation of fluorescent O-(fluoresceinylmethyl)oxime (FMO)- steroid conjugates

Autor:	Yon-Yih Chen, Jonathan Grote, Phillip G. Mattingly, Maciej Adamczyk
Rok vydání:	1999
Předmět:	Magnetic Resonance Spectroscopy Ketone Hydrocortisone Estrone medicine.medical_treatment Clinical Biochemistry Biochemistry Chemical synthesis Steroid chemistry.chemical_compound Endocrinology Hydroxylamine Digitoxin Oximes medicine Organic chemistry Molecular Biology Chromatography High Pressure Liquid Progesterone Fluorescent Dyes Pharmacology chemistry.chemical_classification Estradiol Organic Chemistry Fluoresceins Oxime chemistry Reagent Indicators and Reagents Steroids Norethindrone Enone Nuclear chemistry
Zdroj:	Steroids. 64:283-290
ISSN:	0039-128X
DOI:	10.1016/s0039-128x(99)00004-5
Popis:	The 5 and 6-isomers of O-(fluoresceinylmethyl)hydroxylamine reacted with a representative sample of oxo-steroids (6-oxoestradiol, estrone, norethindrone, cortisol, progesterone, and digitoxin-dialdehyde) to produce O-(fluoresceinylmethyl)oxime conjugates in a single step in 24–84% yield after preparative high performance liquid chromotography.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104d1f35a6ebaa058368498cfa9170a0 https://doi.org/10.1016/s0039-128x(99)00004-5 Zobrazit plný text záznamu Full Text from ScienceDirect