Antibiotic resistance patterns of Escherichia coli isolates from different aquatic environmental sources in León, Nicaragua
| Autor: | Patricia Colque, S. Calderón, Daniel Reyes, Carl Erik Nord, Erick Amaya, Roland Möllby, Margarita Paniagua, Mamun-Ur Rashid, Inger Kühn, Andrej Weintraub |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Cefotaxime Nalidixic acid water Sewage Ceftazidime Nicaragua Microbial Sensitivity Tests Biology Wastewater beta-Lactamases Microbiology resistance Antibiotic resistance Bacterial Proteins Antibiotics Ampicillin Drug Resistance Bacterial medicine Escherichia coli Humans hospital well business.industry Drinking Water General Medicine biochemical phenomena metabolism and nutrition extended-spectrum β-lactamase bacterial infections and mycoses Hospitals Anti-Bacterial Agents Random Amplified Polymorphic DNA Technique Ciprofloxacin Infectious Diseases Gentamicin business Water Microbiology medicine.drug |
| Zdroj: | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases. 18(9) |
| ISSN: | 1469-0691 |
| Popis: | Antibiotic-resistant bacteria have emerged due to the selective pressure of antimicrobial use in humans and animals. Water plays an important role in dissemination of these organisms among humans, animals and the environment. We studied the antibiotic resistance patterns among 493 Escherichia col/isolates from different aquatic environmental sources collected from October 2008 to May 2009 in Leon, Nicaragua. High levels of antibiotic resistance were found in E. coli isolates in hospital sewage water and in eight of 87 well-water samples. Among the resistant isolates from the hospital sewage, ampicillin, chloramphenicol, ciprofloxacin, nalidixic acid, trimethoprim-sulphamethoxazole was the most common multi-resistance profile. Among the resistant isolates from the wells, 19% were resistant to ampicillin, ceftazidime, ceftriaxone, cefotaxime, chloramphenicol, ciprofloxacin, gentamicin, nalidixic acid and trimethoprim-sulphameth-oxazole. E. coli producing ESBL and harbouring bla CTX-M genes were detected in one of the hospital sewage samples and in 26% of the resistant isolates from the well-water samples. The bla CTX-M-9 group was more prevalent in E. coli isolates from the hospital sewage samples and the bla CTX-M-1 group was more prevalent in the well-water samples. |
| Databáze: | OpenAIRE |
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