Presence of the major outer-membrane protein of Chlamydia trachomatis in patients with chronic salpingitis and salpingitis isthmica nodosa with tubal occlusion
| Autor: | Carola Rummel, Heiko Petersen, L.Werner Bader, Thomas Fenner, Stefan Dieterle |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Fallopian Tube Diseases Sexually transmitted disease medicine.medical_specialty animal structures Chlamydia trachomatis Biology medicine.disease_cause Salpingitis medicine Humans Prospective Studies Salpingitis isthmica nodosa Gynecology Tubal ligation Chlamydia Obstetrics and Gynecology medicine.disease female genital diseases and pregnancy complications medicine.anatomical_structure Reproductive Medicine Chronic Disease Female Infertility Female Bacterial Outer Membrane Proteins Fallopian tube |
| Zdroj: | Fertility and Sterility. 70:774-776 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/s0015-0282(98)00248-9 |
| Popis: | Objective: To determine the presence of the major outer-membrane protein of Chlamydia trachomatis in fallopian tube tissue specimens of infertile women with chronic salpingitis and/or salpingitis isthmica nodosa with tubal occlusion. Design: Prospective controlled study. Setting: Department of Obstetrics and Gynecology, University of Bochum, Herne, Germany. Patient(s): Fifty-six consecutive infertile women with histologically documented chronic salpingitis and/or salpingitis isthmica nodosa and bilateral tubal occlusions were evaluated. They were compared with 28 fertile women. Intervention(s): Fallopian tube tissue specimens were taken during reconstructive infertility surgery, including cesarean section and tubal ligation. Main Outcome Measure(s): Detection of the major outer-membrane protein of C. trachomatis in fallopian tube tissue specimens by a direct fluorescent antibody test. Result(s): The major outer-membrane protein of C. trachomatis was found in fallopian tube tissue specimens in 11 of 56 infertile patients (20%) with chronic salpingitis and/or salpingitis isthmica nodosa. The median titer of IgG serum antibodies to Chlamydia was significantly higher in women with the major outer-membrane protein of C. trachomatis than in patients without this antigen. In comparison, the major outer-membrane protein of C. trachomatis was not found in any of the fallopian tube tissue specimens of the control group. Conclusion(s): The presence of the major outer-membrane protein of C. trachomatis is associated with chronic salpingitis and/or salpingitis isthmica nodosa with tubal occlusion. |
| Databáze: | OpenAIRE |
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