| Autor: |
Aloysius, Mark M., Shrivastava, Sanskriti, Rojulpote, Chaitanya, Naseer, Raza, Hanif, Hamza, Babic, Milos, Gentilezza, Kenneth, Boruah, Pranjal K., Pancholy, Samir |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Frontiers in Cardiovascular Medicine. 9 |
| ISSN: |
2297-055X |
| DOI: |
10.3389/fcvm.2022.961160 |
| Popis: |
BackgroundThere is limited insight into the epidemiological characteristics and effect of race and ethnicity on Primary Malignant Cardiac Tumors (PMCTs).ObjectivesComparison of clinical characteristics and cancer-specific survival outcomes of major races in the United States from the Surveillance, Epidemiology and End-Result (SEER) registry.MethodsICD-O-3 codes were used to identify PMCTs for the years 1975 to 2015. Three major races were identified—“White”, “Black”, and “Asian/Pacific Islander”. Cancer-specific survival outcomes were compared using Kaplan-Meier analysis across and amongst races, based on tumor histology. A subgroup analysis of cancer-specific survival was performed between “Hispanics” and “non-Hispanics.”ResultsSeven hundred and twenty patients were identified−47% females and 79% White, mean age at diagnosis (47 ± 20 years). Black patients were significantly younger (39 ± 18 years) and presented more commonly with angiosarcomas (53%). Non-angiogenic sarcomas and lymphomas were the most common tumors in the White (38%) and Asian/Pacific Islander (34%) cohorts. For a median follow-up period of 50 (IQR3-86) months, cancer-specific survival (mean ± SD, in months) was worse in Blacks (9 ± 3) as compared to Whites (15 ± 1) and Asian/Pacific Islander (14 ± 1) (p-value; Black vs. White p = 0.011).ConclusionBlack and non-Hispanic patients have poorer cancer-specific survival in PMCTs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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