A Multicenter Clinical Study of Single-Kidney Transplantation vs En Bloc Transplantation with Kidneys from Deceased Pediatric Donors
| Autor: | Yong Guang Liu, Ming Zhao, Jian Min Hu, Xiao Jin |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Delayed Graft Function Renal function Kaplan-Meier Estimate Postoperative Complications medicine Humans Survival rate Kidney transplantation Retrospective Studies Transplantation Kidney business.industry Incidence Incidence (epidemiology) Graft Survival Infant Retrospective cohort study medicine.disease Kidney Transplantation Tissue Donors Surgery Survival Rate medicine.anatomical_structure Tissue and Organ Harvesting Kidney Failure Chronic Female Graft survival business |
| Zdroj: | Transplantation Proceedings. 51:3252-3258 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2019.06.012 |
| Popis: | Background There are still disputes regarding the choice of surgical approach to harvest organs from pediatric donors for organ recipients. The primary goal of this multicenter, retrospective analysis was to compare outcomes between single-kidney transplantation (SKT) and en bloc kidney transplantation (EBKT). Methods Data from donors and recipients aged 4 to 18 months from 3 transplant centers over 5 year were collected to compare postoperative complications and recoveries of renal function between SKT and EBKT and to determine whether there is a difference in the 1-year patient and kidney survival rate between the 2 groups. Results Between the SKT and EBKT groups, the incidence of delayed graft function was significantly higher in the SKT group than in the EBKT group (44.1% vs 17.3%, P = .03), and there were no significant differences in other complications (47.0% vs 59.0%, P = .36). Moreover, no significant differences were observed for the overall patient survival rate (P = .08) or the overall graft survival rate (P = .71). Conclusions The short-term effects of SKT make it worthy of consideration. For infants aged 4 to 18 months, SKT can provide good results, alleviating the current tense situation in kidney donation. |
| Databáze: | OpenAIRE |
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