Supplementary Figure 4 from Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors

Autor: George Coukos, Gordon J. Freeman, Karen M. Kaluza, Jaikumar Duraiswamy
Rok vydání: 2023
DOI: 10.1158/0008-5472.22395068
Popis: Supplementary Figure 4 - PDF file 28K, Combining �CD25 antibody with PD-1 and CTLA-4 blocking antibodies did not show additional benefit in tumor rejection. Survival of mice inoculated with 0.5 x 106 CT26 tumor cells and injected i.p. �CD25 antibody (PC61, 250 �g) 3 days following tumor inoculation. Tumor size of >200mm3 was defined as lack of survival. Each curve is representative of 3 independent experiments of 12 mice per group (ns, p value not significant)
Databáze: OpenAIRE