Thai plants from Doi Tung: brine shrimp lethality, antioxidative activity and combination effect with L-ascorbic acid
| Autor: | Patcharawan Tanamatayarat, Uthai Sotanaphun, Onoomar Poobrasert |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
DPPH
Brine shrimp Plant Science Ascorbic Acid Biochemistry Antioxidants Analytical Chemistry chemistry.chemical_compound Inhibitory Concentration 50 Crustacea Botany Toxicity Tests Animals Hydrocotyle javanica Plants Medicinal Traditional medicine biology Chemistry Plant Extracts fungi Organic Chemistry Combination index biology.organism_classification Ascorbic acid Thailand Mitrephora wangii Toxicity Lethality |
| Zdroj: | Natural product research. 26(10) |
| ISSN: | 1478-6427 |
| Popis: | Methanolic extracts of 18 Thai plants from Doi Tung, the north of Thailand, were examined for brine shrimp lethality and antioxidative activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In brine shrimp lethality, the highly toxic plant extracts were Mitrephora wangii (LC(50) 14.8 µg mL(-1)) and Hydrocotyle javanica (LC(50) 13.3 µg mL(-1)). The extracts of Sageretia cordifolia, Ulmus lancaefolia and Acer chiangdaoense exhibited highly antioxidative activities with IC(50) values of 6.7, 8.1 and 9.8 µg mL(-1), respectively. Moreover, the extracts of S. cordifolia, U. lancaefolia and A. chiangdaoense have shown slightly synergistic effects (combination index; CI 1) with L-ascorbic acid on DPPH radicals. A number of plants demonstrated either brine shrimp lethality or free radical scavenging activity. |
| Databáze: | OpenAIRE |
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