Fatal intoxication with melperone
| Autor: | S Stein, Achim Schmoldt, Martin Schulz |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
medicine.medical_specialty Melperone Nordazepam Autopsy Pathology and Forensic Medicine Fatal Outcome Antimanic Agents Cause of Death medicine Humans Cause of death Diazepam Cerebral Spinal Fluid business.industry Medical jurisprudence Drug Synergism Carbamazepine Butyrophenones Substance Abuse Detection Suicide Anti-Anxiety Agents Anesthesia Female Homicide business Law Antipsychotic Agents medicine.drug |
| Zdroj: | Forensic Science International. 113:409-413 |
| ISSN: | 0379-0738 |
| DOI: | 10.1016/s0379-0738(00)00201-2 |
| Popis: | Melperone is judged to be a safe neuroleptic drug. Until now there has been no report of a melperone fatality, though it has been used in suicide attempts. We report on a case of a 36-year-old woman where no cause of death could be established at autopsy. Criminological investigation pointed to a homicide by poisoning but also the possibility of a suicide had to be taken in account. The toxicological analysis of blood, cerebral spinal fluid and urine revealed extremely high concentrations of melperone which had never been reported before. Furthermore, diazepam, nordazepam and carbamazepine were detected. To our knowledge, this case is the first melperone fatality. Possible interactions with diazepam and carbamazepine are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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