A novel software platform for volumetric assessment of ablation completeness
| Autor: | Alessandro Rotilio, Katia M. Passera, Ilaria Marre, S. Nahum Goldberg, Tiziana Ierace, Luigi Solbiati, Riccardo Muglia, Marco Solbiati |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Cancer Research lcsh:Medical technology Physiology Computer science medicine.medical_treatment Image processing computer.software_genre ablation 3D rendering 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Software Physiology (medical) Completeness (order theory) medicine Humans Aged Retrospective Studies Aged 80 and over software business.industry 3d rendering Middle Aged Ablation digestive system diseases humanities image processing body regions lcsh:R855-855.5 030220 oncology & carcinogenesis Catheter Ablation Female Data mining business computer ct |
| Zdroj: | International Journal of Hyperthermia, Vol 36, Iss 1, Pp 336-342 (2019) |
| ISSN: | 1464-5157 0265-6736 |
| DOI: | 10.1080/02656736.2019.1569267 |
| Popis: | Purpose: To retrospectively evaluate the accuracy of a novel software platform for assessing completeness of percutaneous thermal ablations. Materials & methods: Ninety hepatocellular carcinomas (HCCs) in 50 patients receiving percutaneous ultrasound-guided microwave ablation (MWA) that resulted in apparent technical success at 24-h post-ablation computed tomography (CT) and with ≥1-year imaging follow-up were randomly selected from a 320 HCC ablation database (2010–2016). Using a novel volumetric registration software, pre-ablation CT volumes of the HCCs without and with the addition of a 5 mm safety margin, and corresponding post-ablation necrosis volumes were segmented, co-registered and overlapped. These were compared to visual side-by-side inspection of axial images. Results: At 1-year follow-up, CT showed absence of local tumor progression (LTP) in 69/90 (76.7%) cases and LTP in 21/90 (23.3%). For HCCs classified by the software as “incomplete tumor treatments”, LTP developed in 13/17 (76.5%) and all 13 (100%) of these LTPs occurred exactly where residual non-ablated tumor was identified by retrospective software analysis. HCCs classified as “complete ablation with |
| Databáze: | OpenAIRE |
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