Child Maltreatment and Clinical Outcome in Individuals at Ultra-High Risk for Psychosis in the EU-GEI High Risk Study
| Autor: | Kraan, Tamar C., Velthorst, Eva, Themmen, Manouk, Valmaggia, Lucia, Kempton, Matthew J., McGuire, Phillip, Van Os, Jim, Rutten, Bart P.F., Smit, Filip, De Haan, Lieuwe, Van Der Gaag, Mark, McGuire, Philip, Valmaggia, Lucia R., Calem, Maria, Tognin, Stefania, Modinos, Gemma, Burger, Nadine, Van Dam, Daniella S., Barrantes-Vidal, Neus, Domínguez-Martínez, Tecelli, Cristóbal-Narváez, Paula, Kwapil, Thomas R., Monsonet-Bardají, Manel, Hinojosa, Lídia, Riecher-Rössler, Anita, Borgwardt, Stefan, Rapp, Charlotte, Ittig, Sarah, Studerus, Erich, Smieskova, Renata, Bressan, Rodrigo, Gadelha, Ary, Brietzke, Elisa, Asevedo, Graccielle, Asevedo, Elson, Zugman, Andre, Ruhrmann, Stephan, Gebhard, Dominika, Arnhold, Julia, Klosterkötter, Joachim, Nordholm, Dorte, Randers, Lasse, Krakauer, Kristine, Naumann, Tanya Louise, Glenthøj, Louise Birkedal, Nordentoft, Merete, De Hert, Marc, Van Winkel, Ruud, Nelson, Barnaby, McGorry, Patrick |
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| Přispěvatelé: | Clinical Psychology, APH - Mental Health, RS: MHeNs - R2 - Mental Health, MUMC+: MA Psychiatrie (3), MUMC+: Hersen en Zenuw Centrum (3), Psychiatrie & Neuropsychologie, RS: MHeNs - R3 - Neuroscience, ANS - Mood, Anxiety, Psychosis, Stress & Sleep, Adult Psychiatry, Epidemiology and Data Science |
| Rok vydání: | 2017 |
| Předmět: |
Male
Child abuse INCREASES clinical outcome Poison control Stress Disorders Post-Traumatic 0302 clinical medicine Risk Factors SCHIZOPHRENIA Child Abuse psychosis Psychological abuse ultra high risk Adult Survivors of Child Abuse PSYCHOPATHOLOGY Justice and Strong Institutions Europe Psychiatry and Mental health Schizophrenia Panic Disorder Female Psychology TRANSITION Psychopathology Clinical psychology Adult medicine.medical_specialty Psychosis SDG 16 - Peace LIFE EVENTS Adolescent DISORDERS Young Adult 03 medical and health sciences medicine Humans COHORT Risk factor Psychiatry METAANALYSIS Depressive Disorder Panic disorder SDG 16 - Peace Justice and Strong Institutions Phobia Social medicine.disease 030227 psychiatry CONVERSION Psychotic Disorders child maltreatment TRAUMATIC EXPERIENCES 030217 neurology & neurosurgery Regular Articles Follow-Up Studies |
| Zdroj: | Kraan, T C, Velthorst, E, Themmen, M, Valmaggia, L, Kempton, M J, McGuire, P, Van Os, J, Rutten, B P F, Smit, F, De Haan, L, Van Der Gaag, M, McGuire, P, Valmaggia, L R, Calem, M, Tognin, S, Modinos, G, Burger, N, Van Dam, D S, Barrantes-Vidal, N, Domínguez-Martínez, T, Cristóbal-Narváez, P, Kwapil, T R, Monsonet-Bardají, M, Hinojosa, L, Riecher-Rössler, A, Borgwardt, S, Rapp, C, Ittig, S, Studerus, E, Smieskova, R, Bressan, R, Gadelha, A, Brietzke, E, Asevedo, G, Asevedo, E, Zugman, A, Ruhrmann, S, Gebhard, D, Arnhold, J, Klosterkötter, J, Nordholm, D, Randers, L, Krakauer, K, Naumann, T L, Glenthøj, L B, Nordentoft, M, De Hert, M, Van Winkel, R, Nelson, B, McGorry, P & EU-GEI High Risk Study 2018, ' Child Maltreatment and Clinical Outcome in Individuals at Ultra-High Risk for Psychosis in the EU-GEI High Risk Study ', Schizophrenia Bulletin, vol. 44, no. 3, pp. 584-592 . https://doi.org/10.1093/schbul/sbw162 EU-GEI High Risk Study 2018, ' Child Maltreatment and Clinical Outcome in Individuals at Ultra-High Risk for Psychosis in the EU-GEI High Risk Study ', Schizophrenia Bulletin, vol. 44, no. 3, pp. 584-592 . https://doi.org/10.1093/schbul/sbw162 Schizophrenia Bulletin, 44(3), 584-592. Oxford University Press Schizophrenia bulletin, 44(3), 584-592. Oxford University Press |
| ISSN: | 1745-1701 0586-7614 |
| Popis: | Background: Child maltreatment has been associated with a wide range of mental disorders in adulthood. Whether child maltreatment is specifically associated with psychosis risk in individuals at ultra-high risk (UHR) for psychosis, or leads to a general vulnerability for overall psychopathology in the UHR stage remains unclear. The present study examines the association between child maltreatment and transition to psychosis and other mental disorders. Methods: The sample consisted of 259 UHR individuals from the EUropean network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) study. Participants were followed-up for 2 years to assess clinical outcome. Clinical outcome was assessed at 6 months, 12 months, and 24 months after baseline. Child maltreatment before the age of 17 years was assessed at baseline. Results: Our findings show that a history of emotional abuse was associated with an increased risk for transition to psychosis (OR = 3.78, 95% CI = 1.17 to 12.39, P = -027). Apart from psychosis, a history of physical abuse was associated with depressive disorder (OR = 4.92, 95% CI = 2.12 to 11.39, P = .001), post-traumatic stress disorder (OR = 2.06, 95% CI = 1.10 to 3.86, P = .023), panic disorder (OR = 2.00, 95% CI = 1.00 to 3.99, P = .048) and social phobia (OR = 2.47, 95% CI = 1.18 to 5.16, P = .016) at follow-up. Conclusion: Our findings suggest that in the UHR stage child maltreatment is a pluripotent risk factor for developing psychosis, depressive disorder, post-traumatic stress disorder (PTSD), panic disorder, and social phobia in adulthood. |
| Databáze: | OpenAIRE |
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