Local infiltration analgesia: a 2-year follow-up of patients undergoing total hip arthroplasty
| Autor: | Anders Lundin, Anders Magnuson, Jan Kuchalik, Anil Gupta |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Quality of life
medicine.medical_specialty Pain medicine Arthroplasty Replacement Hip Analgesic 03 medical and health sciences Postoperative complications 0302 clinical medicine Double-Blind Method Anesthesiology Medicine Humans Pain Management 030212 general & internal medicine Anesthetics Local Adverse effect Aged Aged 80 and over 030222 orthopedics Analgesics Pain Postoperative Morphine business.industry Middle Aged Anesthesiology and Pain Medicine Local anesthetics Anesthesia Local infiltration Original Article Total hip arthroplasty Analgesia business medicine.drug Follow-Up Studies |
| Zdroj: | Journal of Anesthesia |
| ISSN: | 1438-8359 0913-8668 |
| Popis: | Purpose Local infiltration analgesia (LIA) is commonly used for postoperative pain management following total hip arthroplasty (THA). However, the long-term effects of the component drugs are unclear. The aim of our study was to investigate functional outcome, quality of life, chronic post-surgical pain, and adverse events in patients within 2 years of undergoing THA. Methods The study was a secondary analysis of data from a previous larger study. Eighty patients were randomized to receive either intrathecal morphine (Group ITM) or local infiltration analgesia (Group LIA) for pain management in a double-blind study. The parameters measured were patient-assessed functional outcome [using the Hip dysfunction and Osteo-arthritis Outcome Score (HOOS) questionnaire], health-related quality of life [using the European Quality of Life–5 dimensions (EQ-5D) questionnaire and the 36-Item Short Form Health Survey (SF-36) score], and pain using the numeric rating score (NRS), with persistent post-surgical pain having a NRS of > 3 or a HOOS pain sub-score of > 30. All complications and adverse events were investigated during the first 2 years after primary surgery. Results Pain intensity and rescue analgesic consumption were similar between the groups after hospital discharge. No differences were found in HOOS or SF-36 score between the groups up to 6 months after surgery. A significant group × time interaction was seen in the EQ 5D form in favor of the LIA group. No between-group difference in persistent post-surgical pain was found at 3 or 6 months, or in adverse events up to 2 years after surgery. Conclusion Analysis of functional outcome, quality of life, and post-discharge surgical pain did not reveal significant differences between patients receiving LIA and those receiving ITM. LIA was found to be a safe technique for THA during the long-term follow-up. However, it should be noted that these conclusions are based on a limited number of patients. |
| Databáze: | OpenAIRE |
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