Donor–Recipient Height Mismatch Is Associated With Decreased Survival in Pediatric‐to‐Adult Liver Transplant Recipients
| Autor: | Carrie B. Moore, Nader Abraham, Deepak Vikraman, Yuval A. Patel, Qimeng Gao, Mariya L. Samoylova, John Yerxa, Samuel J. Kesseli, Marcelo Cerullo, Andrew S. Barbas, Lisa M. McElroy |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Tissue and Organ Procurement Adolescent medicine.medical_treatment Kaplan-Meier Estimate Liver transplantation Cold Ischemia Time Living Donors medicine Humans Child Survival analysis Retrospective Studies Transplantation Deceased donor Hepatology business.industry Graft Survival Hazard ratio Perioperative Tissue Donors Transplant Recipients Liver Transplantation Surgery Treatment Outcome Adult liver business |
| Zdroj: | Liver Transplantation. 27:425-433 |
| ISSN: | 1527-6473 1527-6465 |
| Popis: | Liver grafts from pediatric donors represent a small fraction of grafts transplanted into adult recipients, and their use in adults requires special consideration of donor size to prevent perioperative complications. In the past, graft weight or volume ratios have been adopted from the living donor liver transplant literature to guide clinicians; however, these metrics are not regularly available to surgeons accepting deceased donor organs. In this study, we evaluated all pediatric-to-adult liver transplants in the United Network for Organ Sharing Standard Transplant Analysis and Research database from 1987 to 2019, stratified by donor age and donor-recipient height mismatch ratio (HMR; defined as donor height/recipient height). On multivariable regression controlling for cold ischemia time, age, and transplantation era, the use of donors from ages 0 to 4 and 5 to 9 had increased risk of graft failure (hazard ratio [HR], 1.81 [P |
| Databáze: | OpenAIRE |
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