Configurable lipid membrane gradients quantify diffusion, phase separations and binding densities
| Autor: | Michael A. Swift, Jose L. Cortez, Kristen A. Muñoz, Chen-min S. Hung, Katherine N. Liu, Babak Sanii |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Directed self assembly
Physics::Biological Physics Surface Properties Chemistry Lipid Bilayers Analytical chemistry Phospholipid General Chemistry Condensed Matter Physics Quantitative Biology::Cell Behavior Diffusion Quantitative Biology::Subcellular Processes chemistry.chemical_compound Chemical physics Phase (matter) lipids (amino acids peptides and proteins) Lipid bilayer phase behavior Diffusion (business) Lipid bilayer Phospholipids Protein Binding |
| Zdroj: | Soft Matter. 11:8217-8220 |
| ISSN: | 1744-6848 1744-683X |
| DOI: | 10.1039/c5sm02013a |
| Popis: | Single-experiment analysis of phospholipid compositional gradients reveals diffusion coefficients, phase separation parameters, and binding densities as a function of localized lipid mixture. Compositional gradients are formed by directed self assembly where rapid-prototyping techniques (i.e., additive manufacturing or laser-cutting) prescribe lipid geometries that self-spread, heal and mix by diffusion. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|