Prevalence, clinical features, and outcomes of SARS-CoV-2 infection in pregnant women with or without mild/moderate symptoms: Results from universal screening in a tertiary care center in Mexico City, Mexico

Autor: Diana A. Aguilar-Ayala, Manuel Cortés-Bonilla, María Yolotzin Valdespino-Vázquez, Sandra Acevedo-Gallegos, Guadalupe Estrada-Gutierrez, Mario Rodríguez-Bosch, J. Arturo Cardona-Pérez, María Antonieta Rivera, A. Cecilia Helguera-Repetto, Carolina Valencia-Contreras, Salvador Espino-Y-Sosa, Juan Carlos Rodriguez-Aldama, Irma A. Coronado-Zarco, Ricardo Figueroa-Damián, Mónica Aguinaga-Ríos, Moisés León-Juárez, Elsa Romelia Moreno-Verduzco, Mario Solis-Paredes, Claudine Irles, Rafael Galván-Contreras, Brenda Frías-Madrid, Isabel Villegas-Mota, César Velasco-Téllez, María de Lourdes Gómez-Sousa, Valeria Avila-Sosa
Rok vydání: 2021
Předmět:
RNA viruses
Viral Diseases
Pulmonology
Coronaviruses
Maternal Health
Tertiary Care Centers
Labor and Delivery
Families
Medical Conditions
Pregnancy
Epidemiology
Medicine and Health Sciences
Prevalence
Mass Screening
Pregnancy Complications
Infectious
Young adult
Children
Pathology and laboratory medicine
Virus Testing
Multidisciplinary
Obstetrics
Pregnancy Outcome
Obstetrics and Gynecology
Gestational age
Medical microbiology
Infectious Diseases
COVID-19 Nucleic Acid Testing
Viruses
Medicine
Female
Maternal death
SARS CoV 2
Pathogens
medicine.symptom
Infants
Research Article
Adult
medicine.medical_specialty
SARS coronavirus
Science
Microbiology
Asymptomatic
Respiratory Disorders
Young Adult
Diagnostic Medicine
medicine
Humans
Mexico
Mass screening
Retrospective Studies
SARS-CoV-2
business.industry
Organisms
Viral pathogens
Infant
Newborn
Biology and Life Sciences
Neonates
COVID-19
Covid 19
medicine.disease
Infectious Disease Transmission
Vertical
Microbial pathogens
Age Groups
Case-Control Studies
Respiratory Infections
People and Places
Birth
Women's Health
Population Groupings
business
Body mass index
Developmental Biology
Zdroj: PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249584 (2021)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0249584
Popis: The perinatal consequences of SARS-CoV-2 infection are still largely unknown. This study aimed to describe the features and outcomes of pregnant women with or without SARS-CoV-2 infection after the universal screening was established in a large tertiary care center admitting only obstetric related conditions without severe COVID-19 in Mexico City. This retrospective case-control study integrates data between April 22 and May 25, 2020, during active community transmission in Mexico, with one of the highest COVID-19 test positivity percentages worldwide. Only pregnant women and neonates with a SARS-CoV-2 result by quantitative RT-PCR were included in this study. Among 240 pregnant women, the prevalence of COVID-19 was 29% (95% CI, 24% to 35%); 86% of the patients were asymptomatic (95% CI, 76%-92%), nine women presented mild symptoms, and one patient moderate disease. No pregnancy baseline features or risk factors associated with severity of infection, including maternal age > 35 years, Body Mass Index >30 kg/m2, and pre-existing diseases, differed between positive and negative women. The median gestational age at admission for both groups was 38 weeks. All women were discharged at home without complications, and no maternal death was reported. The proportion of preeclampsia was higher in positive women than negative women (18%, 95% CI, 10%-29% vs. 9%, 95% CI, 5%-14%, PPP
Databáze: OpenAIRE
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