An introduction of various spectroscopic methods to identifyin vivo metal wear in total knee arthroplasty
| Autor: | Nenad Stojilovic, J. D. Ehrman, Rex D. Ramsier, E.T. Bender, M. W. Kovacik, Justin C. Tokash, I. A. Gradisar |
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| Rok vydání: | 2008 |
| Předmět: |
Male
Materials science Surface Properties Scanning electron microscope Alloy Biomedical Engineering Energy-dispersive X-ray spectroscopy engineering.material Biomaterials Metal X-ray photoelectron spectroscopy Impurity Materials Testing Alloys Humans Prospective Studies Composite material Arthroplasty Replacement Knee Spectroscopy Aged Aged 80 and over Titanium Synovial Membrane Metallurgy Metals and Alloys Titanium alloy Prosthesis Failure Metals Spectrophotometry visual_art Ceramics and Composites engineering visual_art.visual_art_medium Female |
| Zdroj: | Journal of Biomedical Materials Research Part A. :1068-1077 |
| ISSN: | 1552-4965 1549-3296 |
| DOI: | 10.1002/jbm.a.31507 |
| Popis: | While the industrial community already employs multiple surface analytical techniques to study compositional wearing of various metallic and nonmetallic materials, as yet, these methods have not been widely introduced into the biological community. We report on a novel approach, using the industrial spectroscopic techniques of X-ray photoelectron spectroscopy, micro-Raman spectroscopy, and scanning electron microscopy equipped with energy dispersive spectroscopy, to identify the fine wear particulates and other impurities deposited within the knee-joint following total knee arthroplasty. In this study, synovial fluid was extracted from knee-joints scheduled for revision of total knee arthroplasty. The small debris flake formed by centrifugation of the fluid was analyzed using the spectroscopic techniques mentioned above. These nondestructive techniques were successful in identifying numerous micron and submicron sized metallic particulates that appear to emanate from both the prosthetic bearing (articulating) surfaces and from backside (nonarticulating) surfaces, even when gross wearing of the prosthetic device was not detectable by direct visual inspection intraoperatively. Most interesting is that the ratio of the in vivo metallic debris is approximately the same ratio as that of the manufactured alloy, indicating prosthetic wearing as opposed to chemical dissolution. More importantly, using these spectroscopic techniques to probe both the surface and below the surface of the synovial deposits, we identify an inhomogeneous distribution of the wear debris. This indicates the need to use multiple techniques in order to adequately identify the elemental composition of the prosthetic wear material. |
| Databáze: | OpenAIRE |
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