Kisspeptin as a potential biomarker throughout pregnancy
| Autor: | Kai-Lun Hu, Hongcui Zhao, Yang Yu, Rong Li |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
media_common.quotation_subject Fertility Miscarriage Fetal Development 03 medical and health sciences 0302 clinical medicine Kisspeptin Kisspeptins Pre-Eclampsia Pregnancy Internal medicine Placenta medicine Humans 030212 general & internal medicine Gestational Trophoblastic Disease media_common Fetus 030219 obstetrics & reproductive medicine business.industry Oxytocin secretion Obstetrics and Gynecology medicine.disease Abortion Spontaneous medicine.anatomical_structure Endocrinology Reproductive Medicine Female business hormones hormone substitutes and hormone antagonists Biomarkers |
| Zdroj: | European journal of obstetrics, gynecology, and reproductive biology. 240 |
| ISSN: | 1872-7654 |
| Popis: | Kisspeptins are a family of neuropeptides that are critical for the puberty initiation and female fertility. Plasma or serum kisspeptin is mainly derived from the placenta during pregnancy and plasma kisspeptin levels significantly increase across pregnancy. Plasma kisspeptin levels could be used as a potential biomarker for the detection of miscarriage, pre-eclampsia, gestational trophoblastic neoplasia (GTN), and fetal development. Kisspeptin may also be involved in the process of parturition by stimulating oxytocin secretion during term pregnancy. This review discussed the potential use of kisspeptin as a marker across pregnancy and highlighted the unresolved problems in this area. Tweetable abstract: Plasma kisspeptin levels could be used as a potential biomarker across pregnancy. |
| Databáze: | OpenAIRE |
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