The Impact of Hospitalization on Readmission, Institutionalization, and Mortality of People with Dementia: A Systematic Review and Meta-Analysis

Autor: Jana Lehmann, Anika Kaczynski, Jochen René Thyrian, Alexander Esser, Wolfgang Hoffmann, Bernhard Michalowsky, Ina Zwingmann, Nele Sophie Schenk
Jazyk: angličtina
Rok vydání: 2018
Předmět:
medicine.medical_specialty
Activities of daily living
Institutionalisation
epidemiology [Dementia]
therapy [Dementia]
Patient Readmission
03 medical and health sciences
0302 clinical medicine
statistics & numerical data [Patient Discharge]
Medicine
Dementia
Humans
statistics & numerical data [Institutionalization]
030212 general & internal medicine
ddc:610
statistics & numerical data [Patient Readmission]
statistics & numerical data [Hospitalization]
business.industry
General Neuroscience
Incidence (epidemiology)
mortality [Dementia]
Institutionalization
General Medicine
medicine.disease
Readmission rate
Patient Discharge
Hospitalization
Psychiatry and Mental health
Clinical Psychology
Care in the Community
Meta-analysis
Relative risk
Emergency medicine
Geriatrics and Gerontology
business
030217 neurology & neurosurgery
Zdroj: Journal of Alzheimer's disease 64(3), 735-749 (2018). doi:10.3233/JAD-171128
DOI: 10.3233/JAD-171128
Popis: Background People with dementia (PwD) are at a high risk of hospitalization. Hospitals are often not adequately equipped for PwD and discharges often come unexpected. Therefore, PwD are at a risk of adverse outcomes. However, information about those outcomes is rare but crucial for the development of preventive strategies. Objectives To conduct a quantitative systematic review and meta-analyses on the impact of a hospitalization on readmission, institutionalization, and mortality in PwD. To identify factors associated with these outcomes. Methods PubMed, CENTRAL, and ScienceDirect were searched for studies including terms for dementia, hospital, readmission, institutionalization, and mortality. Relevant were assessed by a quality criteria sheet. Results were summarized in a table. Meta-analysis was conducted with Review Manager 5.3. Results The search yielded 1,108 studies; 20 fulfilled the inclusion criteria and 10 studies were eligible for meta-analyses. The incidence and relative risk (RR) of mortality (RR 1.74 CI95 % 1.50, 2.05) and institutionalization (RR: 2.16 CI95 % 1.31, 3.56) of PwD was significantly higher when compared to people without dementia. Results according to readmission rate were inconsistent. Factors significantly associated with the examined adverse outcomes were severity of dementia, number of medications, and deficits in daily living activities. Conclusion Hospitalization of PwD lead to adverse outcomes. An improvement in the identification of and care for PwD in the acute setting as well as in after care in the community setting, especially in the interface between both settings, is required to prevent adverse outcomes in hospitalized PwD.
Databáze: OpenAIRE