Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010
| Autor: | Jill S. Barnholtz-Sloan, Lisa Rogers, Adah S. Zhang, Quinn T. Ostrom, Carol Kruchko, David M. Peereboom |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Cancer Research Pediatrics medicine.medical_specialty Pathology Adolescent Childhood leukemia Epidemiology Population Brain tumor Young Adult 03 medical and health sciences 0302 clinical medicine Neoplasms Prevalence medicine Humans Registries Young adult Child education Survival rate Aged Aged 80 and over education.field_of_study Pilocytic astrocytoma Brain Neoplasms business.industry Age Factors Infant Newborn Infant Cancer Middle Aged Prognosis medicine.disease United States Survival Rate Oncology Child Preschool 030220 oncology & carcinogenesis Female Neurology (clinical) business 030217 neurology & neurosurgery SEER Program |
| Zdroj: | Neuro-Oncology. :now252 |
| ISSN: | 1523-5866 1522-8517 |
| DOI: | 10.1093/neuonc/now252 |
| Popis: | Background Complete prevalence proportions illustrate the burden of disease in a population. This study estimates the 2010 complete prevalence of malignant primary brain tumors overall and by Central Brain Tumor Registry of the United States (CBTRUS) histology groups, and compares the brain tumor prevalence estimates to the complete prevalence of other common cancers as determined by the Surveillance, Epidemiology, and End Results Program (SEER) by age at prevalence (2010): children (0-14 y), adolescent and young adult (AYA) (15-39 y), and adult (40+ y). Methods Complete prevalence proportions were estimated using a novel regression method extended from the Completeness Index Method, which combines survival and incidence data from multiple sources. In this study, two datasets, CBTRUS and SEER, were used to calculate complete prevalence estimates of interest. Results Complete prevalence for malignant primary brain tumors was 47.59/100000 population (22.31, 48.49, and 57.75/100000 for child, AYA, and adult populations). The most prevalent cancers by age were childhood leukemia (36.65/100000), AYA melanoma of the skin (66.21/100000), and adult female breast (1949.00/100000). The most prevalent CBTRUS histologies in children and AYA were pilocytic astrocytoma (6.82/100000, 5.92/100000), and glioblastoma (12.76/100000) in adults. Conclusions The relative impact of malignant primary brain tumors is higher among children than any other age group; it emerges as the second most prevalent cancer among children. Complete prevalence estimates for primary malignant brain tumors fills a gap in overall cancer knowledge, which provides critical information toward public health and health care planning, including treatment, decision making, funding, and advocacy programs. |
| Databáze: | OpenAIRE |
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