Tick-Borne Encephalitis Virus, United Kingdom
| Autor: | Richard Vipond, Daniel P. Carter, Matthew Baylis, Mara S Rocchi, Steven T. Pullan, James S. Lewis, Roger Hewson, Jolyon M Medlock, Maya Holding, Stuart D. Dowall |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Epidemiology Tick-Borne Encephalitis Virus United Kingdom tickborne infections Ixodes ricinus vector-borne infections lcsh:Medicine TBEV 0302 clinical medicine flavivirus 030212 general & internal medicine Phylogeny biology Reverse Transcriptase Polymerase Chain Reaction tick-borne encephalitis louping ill virus Flavivirus Tick-borne encephalitis virus Infectious Diseases RNA Viral Female meningitis/encephalitis Encephalitis Encephalitis Tick-Borne Microbiology (medical) Ixodidae tick-borne encephalitis virus 030231 tropical medicine Enzyme-Linked Immunosorbent Assay Tick Virus lcsh:Infectious and parasitic diseases Encephalitis Viruses Tick-Borne ticks 03 medical and health sciences Louping ill virus parasitic diseases medicine Animals Humans lcsh:RC109-216 viruses sentinel animals Sequence Analysis RNA Research lcsh:R Tick-borne encephalitis Hemagglutination Inhibition Tests biology.organism_classification medicine.disease Virology United Kingdom zoonoses Sentinel Species deer immunological surveillance |
| Zdroj: | Emerging Infectious Diseases EMERGING INFECTIOUS DISEASES Emerging Infectious Diseases, Vol 26, Iss 1, Pp 90-96 (2020) |
| ISSN: | 1080-6059 1080-6040 |
| Popis: | During February 2018–January 2019, we conducted large-scale surveillance for the presence and prevalence of tick-borne encephalitis virus (TBEV) and louping ill virus (LIV) in sentinel animals and ticks in the United Kingdom. Serum was collected from 1,309 deer culled across England and Scotland. Overall, 4% of samples were ELISA-positive for the TBEV serocomplex. A focus in the Thetford Forest area had the highest proportion (47.7%) of seropositive samples. Ticks collected from culled deer within seropositive regions were tested for viral RNA; 5 of 2,041 ticks tested positive by LIV/TBEV real-time reverse transcription PCR, all from within the Thetford Forest area. From 1 tick, we identified a full-length genomic sequence of TBEV. Thus, using deer as sentinels revealed a potential TBEV focus in the United Kingdom. This detection of TBEV genomic sequence in UK ticks has important public health implications, especially for undiagnosed encephalitis. |
| Databáze: | OpenAIRE |
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