Autonomic testing: which value for each cardiovascular test? An observational study

Autor: G. Bax, Eugenio Ragazzi, F. Bellavere, Nino Cristiano Chilelli, Annunziata Lapolla
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Male
Cardiovascular tests
Diabetic neuropathy
Endocrinology
Diabetes and Metabolism

Diagnostic Techniques
Cardiovascular

030204 cardiovascular system & hematology
Cardiovascular
Cardiovascular System
Hypotension
Orthostatic

Autonomic neuropathy
0302 clinical medicine
Endocrinology
Diabetic Neuropathies
Medicine
Medical diagnosis
General Medicine
Middle Aged
Test (assessment)
Diabetes and Metabolism
Cardiovascular Diseases
Cardiology
Female
medicine.symptom
Hypotension
Endocrine
medicine.medical_specialty
Valsalva Maneuver
Orthostatic
Diaphragmatic breathing
030209 endocrinology & metabolism
Autonomic Nervous System
Sensitivity and Specificity
Diagnostic Techniques
Endocrine

03 medical and health sciences
Predictive Value of Tests
Internal medicine
Diabetes mellitus
Internal Medicine
Humans
Postural hypotension
Aged
Autonomic Nervous System Diseases
Diabetic Angiopathies
Reproducibility of Results
business.industry
Dysautonomia
medicine.disease
Diagnostic Techniques
Observational study
Autonomic testing
business
Popis: Cardiovascular autonomic testing is time consuming when adopting the entire Ewing battery of tests, hence, clinicians usually adopt an empirically reduced number of tests which may give controversial results. Our purpose was to examine the reliability of the cardiovascular tests most commonly used in autonomic diagnoses. We tested 334 subjects, from an original group of 3745, who had shown an altered deep breathing test to both Lying to standing and Valsalva manoeuvre, assuming a value of postural hypotension of more than 15 mmHg as a sign of almost true dysautonomia. VM showed the highest sensitivity (85%) and, when coupled to LS, highest specificity (83%). VM could be useful when screening for possible or early autonomic neuropathy, VM + LS is useful as a diagnostic tool for probable or advanced autonomic neuropathy, and VM + LS + PH is useful for certain diagnosis of definite or late stage autonomic neuropathy.
Databáze: OpenAIRE