Is aortic wall shear stress affected by aging? An image-based numerical study with two age groups
| Autor: | Matts Karlsson, Johan Renner, Toste Länne, Jonas Lantz |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Aging medicine.medical_specialty Biomedical Engineering Biophysics Young Adult Age groups Internal medicine medicine.artery Image Processing Computer-Assisted medicine Shear stress Humans Computer Simulation Aorta medicine.diagnostic_test Magnetic resonance imaging Blood flow Middle Aged Magnetic Resonance Imaging Surgery Aortic wall Shear (geology) Hydrodynamics Cardiology Stress Mechanical Shear Strength Image based |
| Zdroj: | Medical Engineering & Physics. 37:265-271 |
| ISSN: | 1350-4533 |
| DOI: | 10.1016/j.medengphy.2014.12.011 |
| Popis: | The size of the larger arteries increases during the entire life, but not much is known about how the change in size affects the blood flow. This study compares the flow field in a group of young males (N = 10, age = 23.5 ± 1.4), with a group of older males (N = 8, age = 58.0 ± 2.8). Aortic geometries were obtained by magnetic resonance imaging, and the aortic blood flow field was computed using computational fluid dynamics. The aortic wall shear stress was obtained from the computations, and it was concluded that time-averaged wall shear stress decreased with increased age, probably as a consequence of increased aortic diameter and decreased stroke volume, which in turn reduces the shear rates in the aorta. However, the oscillatory shear index, which is a measure of the oscillatory nature of the wall shear stress vector, seemed to be unaffected by aging. |
| Databáze: | OpenAIRE |
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