Cancer Death Risk Related to Radiation Exposure from Computed Tomography Scanning Among Testicular Cancer Patients
| Autor: | Sirpa Heinävaara, Eeva Salminen, Hannele Niiniviita, Hannu Järvinen |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Adult Male Cancer Research Neoplasms Radiation-Induced Adolescent Computed tomography Radiation Dosage Effective dose (radiation) Risk Assessment Cohort Studies 03 medical and health sciences Young Adult 0302 clinical medicine Testicular Neoplasms Risk Factors medicine Humans In patient Child Cancer death Testicular cancer Finland medicine.diagnostic_test business.industry Age Factors General Medicine Middle Aged Radiation Exposure medicine.disease University hospital ta3122 Radiation exposure Survival Rate 030104 developmental biology Oncology 030220 oncology & carcinogenesis Ct imaging Nuclear medicine business Tomography X-Ray Computed |
| Zdroj: | Anticancer research. 37(2) |
| ISSN: | 1791-7530 |
| Popis: | Background A study of the computed tomography (CT) imaging related effective doses and radiation-related cancer death risk. Patients and methods Estimate effective doses were computed from CT scans of testicular cancer patients treated and followed-up in Turku University Hospital, South Western Finland. Association between effective doses from follow-up CT scans and radiation-induced cancer death was examined using United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) 2008 formula. Results Mean effective dose per CT abdomen was 9.32 (standard deviation, SD 3.89) mSv and for whole-body CT it was 14.24 (SD 6.84) mSv. During follow-up of 6 years, the patients were estimated to undergo 12 to 14 abdominal/whole-body CTs and the corresponding risk estimates were 0.11 and 1.14, respectively. The risk of estimated radiation-induced cancer deaths (RICD in %) computed for mean effective doses was lower in patients diagnosed at older age, being 0.61 for 10-19 years age and 0.04 for 40-49 years age at the diagnosis. Conclusion Patient radiation exposure in CT imaging is associated with the type of CT device and imaging protocols, which should be periodically updated and reviewed to minimize individual exposure. Using the UNSCEAR modelling 2 % risk for radiation related cancer death was attributed to diagnostic exposure of study patients. Age at the diagnosis was associated with CT imaging related radiation exposure. The highest exposure was estimated to the youngest patients. |
| Databáze: | OpenAIRE |
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