Effect of ethanolic extract of Senecio biafrae on puberty onset and fertility in immature female rat
| Autor: | Richard Simo Tagne, C. Mouokeu, Landry Lienou Lienou, Didiane Mefokou Yemele, Balé Bayala, M.C. Lemfack, Paul Fewou Moundipa, Stephanie Chekem Goka, PB Telefo |
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| Rok vydání: | 2011 |
| Předmět: |
Infertility
medicine.medical_specialty Cholesterol media_common.quotation_subject Uterus Fertility Biology Senecio Body weight medicine.disease biology.organism_classification Senecio biafrae puberty ovaries uterus chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine medicine General Earth and Planetary Sciences Medicinal plants General Environmental Science Puberty onset media_common |
| Zdroj: | Cameroon Journal of Experimental Biology; Vol 6, No 2 (2010) |
| ISSN: | 1816-0573 |
| DOI: | 10.4314/cajeb.v6i2.68528 |
| Popis: | Senecio biafrae is a medicinal plant widely used by traditional healers in the western region of Cameroon for the treatment of woman infertility . In the course of the evaluation of its effect on puberty onset and some physiological parameters of fertility, different doses of its ethanolic extract were orally administered to immature female rats for 30 days. Body, ovarian, uterus weight; uterine, ovarian proteins or cholesterol level as well as data on puberty onset were recorded. A linear increase in the growth rate of all animal was observed throughout the experimental period. From the 27 th day till the end of treatment, the body weight gain of rats treated with 8 mg/kg was significantly increased (p Overall, the present results provide evidence on the estrogenic effect of the ethanolic extract of Senecio biafrae leading to the acceleration of puberty onset in immature female rat. Key words : Fertility; Senecio biafrae ; puberty; ovaries; uterus |
| Databáze: | OpenAIRE |
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