Primary small cell carcinoma of tonsil: A rare case with review of literature
| Autor: | Rajender Negi, Ashish Chaudhury, Kavita Mardi, Lalita Negi, Anita Negi |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Neck mass lcsh:Medicine Small-cell carcinoma stomatognathic system Throat Biopsy otorhinolaryngologic diseases medicine small cell carcinoma medicine.diagnostic_test biology business.industry lcsh:R neuroendocrine carcinoma Chromogranin A General Medicine medicine.disease medicine.anatomical_structure tonsil Tonsil immunohistochemistry biology.protein Synaptophysin Immunohistochemistry medicine.symptom business |
| Zdroj: | Archives of Medicine and Health Sciences, Vol 8, Iss 2, Pp 284-286 (2020) |
| ISSN: | 2321-4848 |
| Popis: | Small cell neuroendocrine carcinoma (NEC) that originates in the tonsil is extremely rare and carries a poor prognosis. Only a few cases of this tumor have been reported so far. Here, we describe a 60-year-old woman who presented with throat pain and dysphagia for about 3 months. Computed tomographic scan revealed a 4 cm × 2 cm tumor with moderate enhancement in the right tonsil and a neck mass in the right level II. A biopsy of the tonsillar mass was performed, and histologic examination revealed oval-to-elongated tumor cells arranged in sheets, having hyperchromatic nuclei, inconspicuous nucleoli, and scant cytoplasm. Prominent nuclear molding and mitotic figures were readily identified. Immunohistochemical staining showed that tumor cells were strongly positive for synaptophysin, chromogranin, and CK7. A diagnosis of primary small cell NEC of the right tonsil was obtained. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|