Worldwide Network for Blood and Marrow Transplantation Recommendations for Establishing a Hematopoietic Cell Transplantation Program, Part I: Minimum Requirements and Beyond

Autor: Adriana Seber, Mary J. Laughlin, Koen Van Biesen, Gregory A. Hale, Naynesh Kamani, Eliane Gluckman, Sebastian Galeano, Shahrukh K. Hashmi, Syed Osman Ahmed, Jeff Szer, Paula Watry, Alok Srivastava, Yoshiko Atsuta, Daniel J. Weisdorf, Parameswaran Hari, Mahmoud Aljurf, John A. Snowden, Hildegard T. Greinix, Dietger Niederwieser, Marcelo C. Pasquini, Carol Doleysh, Jane F. Apperley
Rok vydání: 2019
Předmět:
Zdroj: Biology of Blood and Marrow Transplantation. 25:2322-2329
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2019.05.002
Popis: Hematopoietic cell transplantation (HCT) is a highly complex procedure that requires a dedicated multidisciplinary team to optimize safety. In addition, institutions may have different needs regarding indications based on regional disease prevalence or may have an interest in developing specialized services. Structured recommendations are not commonly available, however. The Transplant Center and Recipient Issues Standing Committee of the Worldwide Network for Blood and Marrow Transplantation (WBMT) organized a structured review of all pertinent elements for establishing a transplantation program. First, we solicited components from committee members and grouped them into domains (infrastructure, staff, cell processing laboratory, blood banking, laboratory, radiology, pharmacy, HLA testing, ancillary services, and quality). Subsequently, reviewers scored each element on a 7-point scale, ranging from an absolute requirement (score of 1) to not required (score of 7). An independent group of 5 experienced transplantation physicians reviewed the rankings. The minimum requirements for establishing any HCT program were identified among elements with mean score of ≤2.0, and specific elements for allogeneic and autologous HCT were identified. Mean scores of >2.0 to 4.0 were classified as preferred recommendation, and mean scores of >4.0 to ≤ 7.0 were considered ideal recommendations for advanced and complex types of transplantation. This structured set of recommendations guides the prioritization of minimum requirements to establish a transplantation program and set the stage for expansion and further development.
Databáze: OpenAIRE