Strategies to Improve the Clinical Outcomes for Direct-to-Consumer Pharmacogenomic Tests
| Autor: | Wojciech Miltyk, Rama K Guggilla, Zahra Kamel-Koleti, Alireza Tafazoli |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
direct-to-consumer pharmacogenomic tests lcsh:QH426-470 Pharmacogenomic Variants Review 03 medical and health sciences 0302 clinical medicine Direct-To-Consumer Screening and Testing Health care Genetics Humans Marketing Precision Medicine Genetics (clinical) Review study business.industry Genetic variants personalized medicine Precision medicine 3. Good health Medical services lcsh:Genetics 030104 developmental biology Phenotype Pharmacogenetics 030220 oncology & carcinogenesis Pharmacogenomics Personalized medicine clinical related outcome business Healthcare system |
| Zdroj: | Genes Genes, Vol 12, Iss 361, p 361 (2021) |
| ISSN: | 2073-4425 |
| Popis: | Direct-to-consumer genetic tests (DTC-GT) have become a bridge between marketing and traditional healthcare services. After earning FDA endorsement for such facilities, several fast-developing companies started to compete in the related area. Pharmacogenomic (PGx) tests have been introduced as potentially one of the main medical services of such companies. Most of the individuals will be interested in finding out about the phenotypic consequences of their genetic variants and molecular risk factors against diverse medicines they take or will take later. Direct-to-consumer pharmacogenomic tests (DTC-PT) is still in its young age, however it is expected to expand rapidly through the industry in the future. The result of PGx tests could be considered as the main road toward the implementation of personalized and precision medicine in the clinic. This narrative critical review study provides a descriptive overview on DTC-GT, then focuses on DTC-PT, and also introduces and suggests the potential approaches for improving the clinical related outcomes of such tests on healthcare systems. |
| Databáze: | OpenAIRE |
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