Value of contrast-enhanced ultrasound in the differential diagnosis of gallbladder lesion
Autor: | Xiao-Hui Qiao, Ying-qian He, Huiping Zhang, Lianfang Du, Min Bai, Jiying Gu |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Adenoma
Adult Male medicine.medical_specialty Contrast enhanced ultrasound Gallbladder disease Gallbladder adenomyomatosis Clinical Practice Study Contrast Media Gallbladder Diseases Gallbladder Sludge Sensitivity and Specificity 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Polyps Conventional ultrasound medicine Humans Prospective Studies Gallbladder cancer Adenomyomatosis Ultrasonography business.industry Gallbladder Gastroenterology General Medicine Middle Aged medicine.disease medicine.anatomical_structure 030211 gastroenterology & hepatology Female Gallbladder Neoplasms Radiology Gallbladder Neoplasm business Gallbladder carcinoma Gallbladder Adenoma Contrast-enhanced ultrasound |
Zdroj: | World Journal of Gastroenterology |
ISSN: | 2219-2840 1007-9327 |
Popis: | Aim To describe contrast-enhanced ultrasound (CEUS) features and evaluate differential diagnosis value of CEUS and conventional ultrasound for patients with benign and malignant gallbladder lesions. Methods This study included 105 gallbladder lesions. Before surgical resection and pathological examination, conventional ultrasound and CEUS were performed to examine for lesions. Then, all the lesions were diagnosed as (1) benign, (2) probably benign, (3) probably malignant or (4) malignant using both conventional ultrasound and CEUS. The CEUS features of these gallbladder lesions were analyzed and diagnostic efficiency between conventional ultrasound and CEUS was compared. Results There were total 17 cases of gallbladder cancer and 88 cases of benign lesion. Some gallbladder lesions had typical characteristics on CEUS (e.g., gallbladder adenomyomatosis had typical characteristics of small nonenhanced areas on CEUS). The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CEUS were 94.1%, 95.5%, 80.0%, 98.8% and 95.2%, respectively. These were significantly higher than conventional ultrasound (82.4%, 89.8%, 60.9%, 96.3% and 88.6%, respectively). CEUS had an accuracy of 100% for gallbladder sludge and CEUS helped in differential diagnosis among gallbladder polyps, gallbladder adenoma and gallbladder cancer. Conclusion CEUS may provide more useful information and improve the diagnosis efficiency for the diagnosis of gallbladder lesions than conventional ultrasound. |
Databáze: | OpenAIRE |
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