Short-term health effects of particulate and photochemical air pollution in asthmatic children
| Autor: | G. Priol, A Grimfeld, Claire Segala, Jocelyne Just, F Sahraoui, Françoise Neukirch |
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| Rok vydání: | 2002 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Time Factors Adolescent Urban Population medicine.drug_class Peak Expiratory Flow Rate Black smoke medicine.disease_cause Risk Assessment Severity of Illness Index Sampling Studies Cohort Studies Age Distribution Environmental health Bronchodilator Confidence Intervals Odds Ratio medicine Humans Particle Size Sex Distribution Child Air quality index Pollen count Asthma Air Pollutants business.industry Incidence Incidence (epidemiology) Particulate pollution medicine.disease Respiratory Function Tests respiratory tract diseases Surgery Disease Progression Female France Seasons Irritation business |
| Zdroj: | European Respiratory Journal. 20:899-906 |
| ISSN: | 1399-3003 0903-1936 |
| DOI: | 10.1183/09031936.02.00236902 |
| Popis: | In a previous panel study in Paris, France, detrimental effects of moderately high levels of winter air pollution on the symptoms and lung function of asthmatic children were demonstrated. A new study was conducted, with the aim of assessing the short-term effects of photo-oxidant and particulate air pollution on childhood asthma during spring and early summer in Paris. Eighty-two medically diagnosed asthmatic children were followed up for 3 months. Outcomes included the incidence and prevalence of asthma attacks, nocturnal cough, supplementary use of beta2-agonists, symptoms of airway irritation, and peak expiratory flow (PEF) value and its variability. The statistical methods controlled for the lack of independence between daily health outcomes, temporal trends and pollen and weather conditions. Black smoke and nitrogen dioxide (NO2) were associated with increases in the occurrence of nocturnal cough and respiratory infections. Ozone (O3) was associated with an increase in the occurrence of asthma attacks and respiratory infections and with changes in lung function, as shown by an increase in PEF variability and a decrease in PEF. Statistically significant interactions were demonstrated between O3 and temperature and between O3 and pollen count for asthma attacks. O3 levels had a greater effect on additional bronchodilator use and on irritations of the eyes, nose and throat on days on which no steroids were used. Particulate matter was associated with eye irritation only. This study showed that, although within international air quality standards, the prevailing levels of photo-oxidant and particulate pollution in spring and early summer had measurable short-term effects on children with mild-to-moderate asthma. |
| Databáze: | OpenAIRE |
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