First trimester placental vascular indices and volume by three-dimensional ultrasound in pre-gravid overweight women
| Autor: | F.J. Sun, H.T. Chang, Chen Cp, C.-Y. Chen |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Placenta Overweight Ultrasonography Prenatal 03 medical and health sciences Imaging Three-Dimensional 0302 clinical medicine Pregnancy medicine.artery medicine Humans Obesity Prospective Studies Uterine artery Three dimensional ultrasound 030219 obstetrics & reproductive medicine Obstetrics business.industry Confounding Obstetrics and Gynecology Confidence interval Pregnancy Complications Pregnancy Trimester First First trimester 030104 developmental biology medicine.anatomical_structure Reproductive Medicine Case-Control Studies Female medicine.symptom business Body mass index Developmental Biology |
| Zdroj: | Placenta. 80:12-17 |
| ISSN: | 0143-4004 |
| DOI: | 10.1016/j.placenta.2019.03.014 |
| Popis: | Objectives To investigate changes of placental vascular indices and volume in pre-gravid overweight Chinese women during the first trimester using three-dimensional power Doppler ultrasound. Methods This was a prospective observational study of the morphology of placentas in pre-gravid overweight (body mass index (BMI) ≥ 24 kg/m2) and non-overweight (BMI Results Of the 429 pregnant women enrolled, 68 (15.9%) were pre-gravid overweight. Placental VFI was significantly lower in the overweight group (p = 0.037). Conversely, placental volume was significantly larger in the overweight group (p = 0.044), and uterine artery PI was significantly higher in the overweight group (p = 0.021). After adjustments for confounding factors, there were still significant differences in placental VFI (unstandardized coefficient (B) −0.666, 95% confidence interval (CI) −1.306 – (−0.025)), placental volume (B 2.458, 95% CI 0.071–4.844), and uterine artery PI (B 0.152, 95% CI 0.030–0.274) between the two groups. Conclusions Placental vascular indices using three-dimensional power Doppler ultrasound can provide an insight into placental vascularization in pre-gravid overweight women in early pregnancy. Alterations in placental VFI, placental volume, and uterine artery PI occur during the first trimester in pre-gravid overweight women. |
| Databáze: | OpenAIRE |
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