Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations
| Autor: | Eric M. Leroy, J. P. Akue, Dieudonné Nkoghe, Jean-Paul Gonzalez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male Rural Population medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine Adolescent lcsh:RC955-962 Plasmodium falciparum Prevalence Parasitemia Biology Environment Asymptomatic Giemsa stain lcsh:Infectious and parasitic diseases parasitic diseases medicine Humans lcsh:RC109-216 Gabon Malaria Falciparum Child Aged Aged 80 and over Research Middle Aged medicine.disease biology.organism_classification Carriage Infectious Diseases Tropical medicine Immunology Carrier State Female Parasitology medicine.symptom Malaria Demography |
| Zdroj: | Malaria Journal Malaria Journal, Vol 10, Iss 1, p 33 (2011) |
| Popis: | Background Malaria may be perennial or epidemic in sub-Saharan Africa, and its transmission may be stable or unstable, depending on the region. The prevalence of asymptomatic Plasmodium falciparum carriage is poorly documented in Gabon. A large survey of P. falciparum infection was conducted in asymptomatic individuals living in rural Gabon. Methods Two hundred and twenty-two villages were randomly selected in the nine administrative regions. With the participants' informed consent, blood samples were collected for thick and thin blood film examination after 20% Giemsa staining. Prevalence rates were calculated per village, per region and per ecosystem, and nationwide. Demographic risk factors were identified with STATA software version 9.0. Significance was assumed at p < 0.05. Results and discussion The prevalence of P. falciparum in adults was 6.2% (269/4342) nationwide, with a maximum of 37.2% in one village; a linear decrease was observed with increasing age (p = 0.045). Only 5% of the 399 children from forest areas tested positive. The prevalence was significantly higher in forest areas (7%) than in savannah (4%) and lakeland (2.5%). Within the forest region, the prevalence was significantly higher in forest grassland (10.9%) than in the mountain forest (3.5%), interior forest (6.8%) and north-eastern forest (4.5%). Conclusion Plasmodium falciparum carriage remains high among adults in rural Gabon. Control measures must be adapted to the region and ecosystem. Routine treatment of asymptomatic individuals should be considered. |
| Databáze: | OpenAIRE |
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