Consideration on Some Hormone Binding Proteins Patterns During Pregnancy

Autor: Mithal Hassan, Ilham Hamdi, M A Al-Awqati, Muna M. Al-Zaid, Sanaa El-Adawi, N. Miller
Rok vydání: 1991
Předmět:
Zdroj: Hormone and Metabolic Research. 23:85-87
ISSN: 1439-4286
0018-5043
DOI: 10.1055/s-2007-1003620
Popis: Serum concentrations of sex hormone binding globulin, transcortin, thyroxine binding globulin, transthyretin together with retinol binding protein, ceruloplasmin, transferrin and albumin were measured sequentially in pregnant women in order to derive more definite suppositions relating to the prime function of hormone binding proteins. Thus, the fact that except for transthyretin all other specific hormone binding proteins exhibited appreciable but significantly variable increases would suggest: a) the apparent existence of more complex mechanisms regulating protein metabolism during pregnancy than hitherto postulated (i.e. the general notion of an integrated estrogen influence); b) a major and distinctive role for each of the hormone binding proteins is plausible since alterations in hormonal requirements by the fetus as pregnancy progresses can not be provided by the almost constant transplacental transfer rate of the "free" hormone moiety.
Databáze: OpenAIRE