Tuberculosis diagnosed by PCR analysis of synovial fluid
| Autor: | Kenichi Gemba, Takumi Kishimoto, Sae Wada, Nobukazu Fujimoto, Yasuhiro Fujii, Shinji Ozaki, Atsushi Yao, Yoshifumi Namba, Katsuichiro Ono |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
musculoskeletal diseases
Microbiology (medical) Male medicine.medical_specialty Pathology Tuberculosis Knee Joint medicine.medical_treatment Polymerase Chain Reaction Tuberculosis Osteoarticular Mycobacterium tuberculosis Diagnosis Differential Young Adult Medical microbiology Biopsy Synovial Fluid medicine Synovial fluid Humans Pharmacology (medical) Lymph node medicine.diagnostic_test biology business.industry Arthrocentesis Tuberculosis Pleural medicine.disease biology.organism_classification Pleural Effusion Infectious Diseases medicine.anatomical_structure Differential diagnosis business |
| Zdroj: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 16(1) |
| ISSN: | 1437-7780 |
| Popis: | Tuberculosis is a leading cause of mortality due to an infectious agent worldwide. It often affects multiple organs by hematogenous spread of Mycobacterium tuberculosis, but knee-joint involvement is extremely rare, comprising approximately 0.1% of all forms of tuberculosis. We present a case of tuberculous pleuritis with knee-joint involvement. Cytological and biochemical analysis of the pleural fluid and a biopsy specimen of the cervical lymph node indicated tuberculosis, but a definitive diagnosis was not given. A confirmed diagnosis was finally obtained through PCR analysis of the synovial fluid. Tuberculosis should be included in the differential diagnosis in patients with persistent pain and swelling of the knee. PCR analysis of the synovial fluid is a quick and useful method for the diagnosis. |
| Databáze: | OpenAIRE |
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