Predicting survival in out-of-hospital cardiac arrest patients undergoing targeted temperature management: The Polish Hypothermia Registry Risk Score
| Autor: | Agnieszka Tycińska, Agnieszka Nazaruk, Elżbieta Kremis, Konrad Koza, Grzegorz Opolski, Beata Średniawa, Ewa Szczerba, Barbara Zawiślak, Magdalena Niedziela, Łukasz Kołtowski, Wiesław Puchalski, Michal Ordak, Joanna Wolska, Robert Ryczek, Magdalena Czajkowska, Robert Kowalik, Janina Stępińska |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Population Hypothermia 030204 cardiovascular system & hematology Return of spontaneous circulation Targeted temperature management Out of hospital cardiac arrest 03 medical and health sciences 0302 clinical medicine Hypothermia Induced Risk Factors Internal medicine Medicine Humans Cardiopulmonary resuscitation Registries education Aged Retrospective Studies education.field_of_study Framingham Risk Score business.industry Area under the curve Temperature General Medicine Middle Aged Cardiopulmonary Resuscitation Treatment Outcome Emergency medicine Cardiology Original Article Poland medicine.symptom Cardiology and Cardiovascular Medicine business Out-of-Hospital Cardiac Arrest |
| Zdroj: | Cardiol J |
| Popis: | Background: Prompt reperfusion and post-resuscitation care, including targeted temperature management (TTM), improve survival in out-of-hospital cardiac arrest (OHCA) patients. To predict inhospital mortality in OHCA patients treated with TTM, the Polish Hypothermia Registry Risk Score (PHR-RS) was developed. The use of dedicated risk stratification tools may support treatment decisions. Methods: Three hundred seventy-six OHCA patients who underwent TTM between 2012 and 2016 were retrospectively analysed and whose data were collected in the Polish Hypothermia Registry. A multivariate logistic regression model identified a set of predictors of in-hospital mortality that were used to develop a dedicated risk prediction model, which was tested for accuracy. Results: The mean age of the studied population was 59.2 ± 12.9 years. 80% of patients were male, 73.8% had shockable rhythms, and mean time from cardiac arrest (CA) to cardiopulmonary resuscitation (CPR) was 7.2 ± 8.6 min. The inputs for PHR-RS were patient age and score according to the Mild Therapeutic Hypothermia (MTH) Scale. Criteria for the MTH score consisted of time from CA to CPR above 10 min, time from CA to the return of spontaneous circulation above 20 min, in-hospital CA, unwitnessed CA, and non-shockable rhythm, each counted as 1 point. The predictive value of PHR-RS was expressed as an area under the curve of 0.74. Conclusions: PHR-RS is one of the simplest and easiest models to use and enables a reliable prediction of in-hospital mortality in OHCA patients treated with TTM. |
| Databáze: | OpenAIRE |
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